Extranodal marginal zone lymphoma of mucosa associated lymphoid tissue arising in the pleura
Keywords:
Lymphoma, B-Cell, Marginal Zone, MALT LymphomaAbstract
A 77-year-old Haitian woman complained of two months history of cough and left upper quadrant abdominal pain. She had a remote history of tuberculosis that was treated back in Haiti many years ago. Imaging studies showed a left pleural effusion with posterior pleural thickening as well as lymphadenopathy in the left hilum and left supraclavicular area. The Pleural biopsy was consistent with extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (EMZL/MALT). The supraclavicular lymph node also showed partial involvement by EMZL/MALT but was largely effaced by non-necrotizing granulomatous inflammation. Culture from this lymph node grew Mycobacterium tuberculosis complex. Primary pleural lymphoma is a rare entity and to the best of our knowledge only ten cases of pleural EMZL/MALT have been reported.We report a new case and a review of literature.Â
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12. Kawahara K, Sasada S, Nagano T, Suzuki H, Kobayashi M, Matsui K, Takata K, Yoshino T, Michida T, Iwasaki T. Pleural MALT Lymphoma diagnosed on thoracoscopic resection under local anesthesia using an insulation-tipped diathermic knife. Pathology International. 2008; 58(4), 253- 6.
13. Motta G, Conticello C, Amato G, Moschetti G, Colarossi C, Cosentino S, et al. Pleuric presentation of extranodal marginal zone lymphoma of mucosa-associated lymphoid tisse: a case report and a review of the literature. 2010; 92(2), 369- 73.
14. Barahona M L, Duenas V P, sanchez M T, Plaza B V. Primary mucosa-associated lymphoid tissue lymphoma as a pleural mass. The British Journal of Radiology. 2011; 84(1008), e229-e231.
2. Chen YB, Rahemtullah A, Hochberg E. Primary Effusion Lymphoma. The Oncologist. 2007; 12(5), 569- 76.
3. Nkatsuka SI, Yao M, Hoshida Y, Yamamoto S, Luchi K, Aozasa K. Pyothorax-associated Lymphoma: A Review of 106 Cases. Journal of Clinical Oncology. 2002; 20(20), 4255- 60.
4. Issacson P G, Chott A, Nakamura S, Muller-Hermelink H K, Harris N L, Swerdlow S H. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue (IARC WHO Classification of Tumours). s.l. : The International Agency for Research on Cancer. 2008: 214
5. Vega F, Padula A, Valbuena J R, Stancu M, Jones D, Medeiros L J. Lymphoma Involving the Pleura: A Clinicopathologic study of 34 Cases Diagnosed by Pleural Biopsy. Arch Pathol Lab Med. 2006; 130 (10), 1497- 502.
6. Kodama K, Yokose T, Takahashi K, Minami H, Nagai K, Matsuno Y, et al. Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue in the lung: a report of a case with pleural dissemination. Lung Cancer. 1999; 24, 175- 8.
7. Ahmad H, Pawade J, Falk S, Morgan J A, Balacumaraswami L. Primary pleural lymphomas. Thorax, 2003; 58, 908- 9.
8. Gomyo H, Kajimoto K, Maeda A, Mizuno I, Funada Y, Koizumi T, Fukui E, Hanioka K, Ogura M, Murayama T. t(14;18)(q32;q21)-bearing pleural MALT lymphoma with IgM paraproteinemia: Value of detection of specific cytogenetic abnormalities in the differential diagnosis of MALT lymphoma and lymphoplasmacytic lymphoma. Hematology. 2007;12(4), 315- 8.
9. Nakarsuka S I, Nagano T, Kimura H, Hanada S, Inoue H, Iwata T. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type arising in the pleura with pleural fibrous plaques in a lathe worker. Annals of Diagnostic Pathology. 2012; 16(3), 224- 9.
10. Hirai S, Hamanaka Y, Mitsui N, Morifuji J, Sutoh M. Primary Malignant Lymphoma Arising in the Pleura without Preceding Long-standing Pyothorax. Ann Thorac Cardiovasc Surg. 2004; 10(5), 297-300.
11. Mitchell A, Meunier C, Ouellette D, Colby T. Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue With Initial Presentation in the Pleura. Chest. 2006; 129(3), 791- 4.
12. Kawahara K, Sasada S, Nagano T, Suzuki H, Kobayashi M, Matsui K, Takata K, Yoshino T, Michida T, Iwasaki T. Pleural MALT Lymphoma diagnosed on thoracoscopic resection under local anesthesia using an insulation-tipped diathermic knife. Pathology International. 2008; 58(4), 253- 6.
13. Motta G, Conticello C, Amato G, Moschetti G, Colarossi C, Cosentino S, et al. Pleuric presentation of extranodal marginal zone lymphoma of mucosa-associated lymphoid tisse: a case report and a review of the literature. 2010; 92(2), 369- 73.
14. Barahona M L, Duenas V P, sanchez M T, Plaza B V. Primary mucosa-associated lymphoid tissue lymphoma as a pleural mass. The British Journal of Radiology. 2011; 84(1008), e229-e231.
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05-05-2015
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Malek A, Lee JC. Extranodal marginal zone lymphoma of mucosa associated lymphoid tissue arising in the pleura. Ann of Pathol and Lab Med [Internet]. 2015 May 5 [cited 2024 Nov. 22];2(2):C66-70. Available from: http://pacificejournals.com/journal/index.php/apalm/article/view/176
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Copyright (c) 2015 Anita Malek, John Cho Lee
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