A Case of Clear Cell Sarcoma of Kidney in An Adult: An Extremely Rare Presentation
DOI:
https://doi.org/10.21276/apalm.2003Keywords:
Clear cell sarcoma of the kidney (CCSK), Immunohistochemistry (IHC), Kidney.Abstract
Clear cell sarcoma of the kidney (CCSK) is a malignant renal tumor of childhood with a propensity to metastasize to bone and other organs. It is extremely rare in adults, must be differentiated from clear cell carcinoma of kidney which is more common in adults. We report a case of CCSK in a 45 year old female, confirmed by Immunohistochemistry (IHC) & managed with radical nephrectomy. The aim of this case report is to increase the awareness about this entity in adults with brief review of relevant literature.
References
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11. Ueno-Yokohata H. et al. Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney. Nat. Genet. 2015; 47: 861–63.
12. Roy, A., Kumar, V., Zorman, B., Fang, E., Haines, K. M., Doddapaneni, H., Parsons, D. W. Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nature Communications. 2015; 6: 8891.
2. Amin MB, de Peralta-Venturina MN, Ro JY, El- Naggar A, Mackay B, Ordonez N. Clear cell sarcoma of kidney in an adolescent and in young adults; a report of four cases with ultrastructural, immunohistochemical, and DNA flow cytometric analysis. Am J Surg Pathol. 1999 Dec; 23(12):1455- 63.
3. Adanani A, Lalid R, Bouklata S, Ajana A, Hammani L, Imani F. Clear cell sarcoma of kidney in an adult: a case report. J Radiol. 2006; 87:136-8.
4. Benchekroun A, Zannoud M, el Alj HA, Nouini Y, Marzouk M, Faik M. Clear cell sarcoma of the kidney: three case reports. Prog Urol. 2002; 12(3):469-73.
5. Lanka K, Bhramaramba K, Venkata Ramana P, Sunethri P. Clear cell sarcoma of kidney in an adult: an extremely rare case. Int Surg J 2015; 2:289-91.
6. Beckwith JB. Wilms’ tumor and other renal tumors of childhood: a selective review from the National Wilms’ Tumor Study Pathology Center. Hum Pathol. 1983; 14:481-92.
7. Morgan E, Kidd JM. Undifferentiated sarcoma of the kidney: a tumor of childhood with histopathologic and clinical characteristics distinct from Wilm’s tumor. Cancer 1978; 42:1916-21.
8. Marsden HB, Lawler W. Bone metastasizing renal tumour of childhood: histopathological and clinical review of 38 cases. Vir- chows Arch [A] 1980; 387:341-51.
9. Mirkovic J, Calicchio M, Fletcher C D & Perez-AtaydeR .Diffuse and strong cyclin D1 immunoreactivity in clear cell sarcoma of the kidney, Histopathology 2015; 67: 306–12.
10. Haas JE, Bonadio JF, Beckwith JB. Clear Cell Sarcoma of the Kidney with emphasis on ultrastructural studies. Cancer 1984; 54:2978-2987.
11. Ueno-Yokohata H. et al. Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney. Nat. Genet. 2015; 47: 861–63.
12. Roy, A., Kumar, V., Zorman, B., Fang, E., Haines, K. M., Doddapaneni, H., Parsons, D. W. Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nature Communications. 2015; 6: 8891.
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17-09-2018
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Vakani PN, Maheshwari M, Maheshwari J, Agarwal A, Patel P, Shah C. A Case of Clear Cell Sarcoma of Kidney in An Adult: An Extremely Rare Presentation. Ann of Pathol and Lab Med [Internet]. 2018 Sep. 17 [cited 2024 Nov. 21];5(9):C131-133. Available from: http://pacificejournals.com/journal/index.php/apalm/article/view/2003
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Copyright (c) 2018 Pragya Nirav Vakani, Mukesh Maheshwari, Jainil Maheshwari, Anshul Agarwal, Pragnesh Patel, Chandresh Shah
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