Multiple cutaneous metastasis of sacral chordoma, mimicking neurofibromas clinically
Keywords:
Cutaneous metastasis, Sacral Chordoma, NeurofibromaAbstract
Chordoma is a rare primary bone tumor of notochordal origin, constituting 1-4% of malignant primary bone tumors. Chordomas are slow growing tumors and show aggressive local extension, multiple recurrences and metastasis. Cutaneous metastasis of chordoma is very rare. We report a case of a 61-year-old man presenting with multiple cutaneous metastasis of primary sacral chordoma.
DOI:10.21276/APALM.1753
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10. Oakley GJ, Fuhrer K, Seethala RR. Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis. Mod Pathol. 2008;21:1461-1469.
2. Horwitz T. Chordal ectopia and its possible relationship to chordoma. Arch Pathol. 1941; 31:354-362.
3. Chambers PW, Schwinn CP. Chordoma: a clinicopathologic study of metastasis. Am J Clin Pathol. 1979;72:765-776.
4. Su WP, Louback JB, Gagne EJ, et al. Chordoma cutis: a report of nineteen patients with cutaneous involvement of chordoma. J Am Acad Dermatol. 1993;29:63-66.
5. Collins GR, Essary L, Strauss J, et al. Incidentally discovered distant cutaneous metastasis of sacral chordoma: a case with variation in S100 protein expression(compared to the primary tumor) and review of the literature. J Cutan Pathol. 2012;39: 637-643.
6. Ruiz HA, Goldberg LH, Humphreys TR, et al. Cutaneous metastasis of chordoma. Dermatol Surg. 2000;26:259.
7. Layfield LJ. Cytologic differential diagnosis of myxoid and mucinous neoplasms of the sacrum and parasacral soft tissues. Diagn Cytopathol. 2003;28:264-271.
8. Jambhekar NA, Rekhi B, Thorat K, et al. Revisiting chordoma with brachiury ‘‘a new age’’ marker. Analysis of a validation study of 51 cases. Arch Pathol Lab Med. 2010;134: 1181-1187.
9. Gagne EJ, Su WP. Chordoma involving the skin: an immunohistochemical study of 11 cases. J Cutan Pathol. 1992;19:469-475.
10. Oakley GJ, Fuhrer K, Seethala RR. Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis. Mod Pathol. 2008;21:1461-1469.
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Published
28-04-2018
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Narang NC, Narang S, Diwaker P. Multiple cutaneous metastasis of sacral chordoma, mimicking neurofibromas clinically. Ann of Pathol and Lab Med [Internet]. 2018 Apr. 28 [cited 2024 Dec. 27];5(4):C65-67. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/1753
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Copyright (c) 2018 Neha Chopra Narang, Salil Narang, Preeti Diwaker
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