Histopathological Study of Infectious Granulomatous Skin Lesions
DOI:
https://doi.org/10.21276/apalm.1874Keywords:
Granuloma, histopathology, leprosy, tuberculosis.Abstract
Background: Granulomas are the commonest lesions that the pathologists come across in routine practice. Granulomatous inflammation is a distinctive pattern of chronic inflammation that is encountered in a number of infectious and non-infectious conditions. A definitive diagnosis made by demonstration of the etiological agent is essential, which will bear an impact on patient management and outcome.
Methods: This is a retrospective study considering the cases of 2 years. The cases diagnosed as infectious granulomatous skin lesions by clinical presentation, histopathological study of skin biopsies of such patients attending our hospital since July 2010 to July 2012 were included in the study. Clinical history and relevant data were obtained from respective requisition forms of biopsies received.
Results: The study includes 67 cases. A male predominance was noted with 47(70.14%) cases while females constituted 20(29.85%) cases .The study shows that 80% of cases are distributed between 21 to 50 yrs of age while the prevalence of infectious granulomatous dermatoses is highest in the age group of 21-30 yrs. Among the different types of infectious granulomatous dermatoses, leprosy contributed to the major etiology, followed by tuberculosis of skin, leishmaniasis and actinomycosis.
Conclusion: Clinical data with the laboratory workup and special stains together are needed for the definitive diagnosis and management of patients with granulomatous lesions. Cooperation between clinician and pathologist is more important in the field of skin disease than in almost any other field if the patient is to derive the greatest benefit from the biopsy.
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Copyright (c) 2018 Ratnakar M Potekar, Anita P Javalgi, Lynda Dennis Rodrigues, Raga Sruthi Dwarampudi
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