Lymphoid Blast Crisis in a Case of Paediatric Chronic Myeloid Leukaemia
An Unusual Presentation of an Uncommon Malignancy
DOI:
https://doi.org/10.21276/apalm.1914Keywords:
Acute Leukaemia, Blast Crisis, Paediatric Chronic Myeloid Leukaemia, SplenomegalyAbstract
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm in which the granulocytes are the major proliferative component and is characterised by the chromosomal translocation t(9;22)(q34.1;q11.2) leading to the formation of Philadelphia chromosome (Ph) containing the BCR-ABL1 fusion gene. This entity is quite rare in paediatric age group and even unusual is a child presenting for the first time in an accelerated or blast crisis. Here we unfold an noteworthy case of a 9 year old school going child presenting with complains of vague abdominal distension who on further evaluation was found to be living through leukaemia.
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Copyright (c) 2018 K V Vinu Balraam, Venkatesan Somasundaram, Nidhi Garg, Sanjeevan Sharma, Sampath K S, Reena Bharadwaj
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