Diagnostic Evaluation of Cervical Lymphadenopathy in FNAC Samples
Case Based Study in A Rural Tertiary Care Hospital
DOI:
https://doi.org/10.21276/apalm.1935Keywords:
Cervical Lymphnode, FNAC, Reactive, Granuloma, MetastasisAbstract
Background: Nowadays lymphadenopathy is a common clinical problem and it may be in a form of localized, limited, or generalized. Cervical lymphadenopathy can be due to infections, malignancies, autoimmune disorders and other miscellaneous conditions. To diagnose lymphadenopathy in a short time, a simple, cost-effective outpatient procedure Fine needle aspiration cytology (FNAC) is necessary. FNAC is an accurate procedure to diagnose lymphadenopathy cases. The purpose of the study was to evaluate the results of FNAC of nodes especially cervical lymphnodes in our institution.
Methods: A retrospective analysis of cervical lymphadenopathy cases reported by FNAC procedure over the period of six months in Department of Pathology. Smears were stained with four different stains including Hematoxylin and Eosin stain, Papaniculaou stain and Giemsa stain. In suspected cases of Tuberculosis special stain like Ziehl-neelsen were performed
Result: In this study age of the patient varied between 1 to 70 years. Most of the cases were benign in which reactive lymphoid hyperplasia was the leading one. The remaining cases were metastatic carcinoma which includes poorly differentiated carcinoma with unknown primary, squamous cell carcinoma (SCC) (Primary from carcinoma cervix, cheek and tongue), adenocarcinoma (Primary from lung and gastrointestinal tract) and an interesting case of follicular neoplasm of thyroid.
Conclusion: Cytology has a high efficacy of diagnosis in patients with cervical lymphadenopathy. It also has the advantage of being able to predict the primary site (where origin of the tumor is unknown) in many cases. It should be considered as an important component of preoperative/pretreatment diagnosis.
References
2. Mukul P, Kusum B, Biraj K.D, Anupam H. A clinicopathological evaluation of cervical lymphadenopathy in children (0-14 Years) by fine needle aspiration cytology and histopathological examination - A hospital based study. National Journal of Otorhinolaryngology and Head & Neck Surgery, Vol. 2(11) No. 2, August 2014
3. Babu GS, Gayathri R, Bina K et al. Cytohistopathological evaluation of the cervical lymph nodes by fine needle aspiration cytology. Journal of Cranio-Maxillo-Facial surgery,2014;3:101-5
4. Moinul HST. Evaluation of fine needle aspiration cytology (FNAC) of lymph node in Mymensingh. Mymensingh Medical Journal 02/2003; 12(1):33-5.
5. Jonas TJ, Nicole CS. Fine-Needle Aspiration of Neck Masses. http://emedicine.medscape.com/article/1819862-overview#a8.
6. Robert F. Lymphadenopathy: Differential Diagnosis and Evaluation. American Family Physician Journal. 1998 Oct 15;58(6):1313-1320
7. Maria I, Viggo B, Christoffer HH. Evaluation of cervical lymphadenopathy in children: advantages & drawbacks of diagnostic methods. Danish Medical Journal, 60/8. Aug 3013: 1-3
8. V Koo, TF Lioe, RAJ Spence. Fine needle aspiration cytology (FNAC) in the diagnosis of granulomatous lymphadenitis. Ulster Medical Journal, 2006; 75(1)59-64.
9. Muhammad MM and Mulazim H B. Evaluation for Granulomatous Inflammation on Fine Needle Aspiration Cytology Using Special Stains. Pathology Research International Volume 2011, Article ID 851524, 8 pages
10. Anne R. W, Sadhana D. M, Sabiha A. M. FNAC in the diagnosis of lymph node malignancies: A simple and sensitive tool. Indian Journal of Medical Paediatric Oncology. 2012 Jan-Mar; 33(1): 21–24.
11. Madhavi M, Durga S, Arjun R J. Cervical lymphadenopathy – an unusual presentation of carcinoma of the cervix: a case report. Journal of Medical Case Reports 2008, 2:252.
12. Ghazala M, Amit K S, Mahboob H et al. Cytological evaluation of enlarged lymph nodes in metastatic disease: A hospital-based assessment. Clinical cancer investigating journal. DOI: 10.4103/2278-0513.152736
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