Histopathological Evaluation of Tumours And Cysts of The Epidermis and Dermal Adnexae in a Tertiary Care Hospital
DOI:
https://doi.org/10.21276/apalm.1990Keywords:
Squamous cell carcinoma, Basal cell carcinoma, Adnexal tumourAbstract
Background: Skin tumours are a challenging group of conditions ,it is difficult to classify and these are diagnosed chiefly by histopathology. The aim of our study was to analyze the incidence and classify the histopathological pattern of tumours and cysts of the epidermis and dermal appendages.
Methods: The current study was a retrospective observational study of epidermal and adnexal tumours and cysts over a period of five and half years from January2007 to December 2012 reported in the department of Pathology ,SMVMCH,Pondicherry over a 5 year period from were analysed and correlated statistically.
Result: Out of 160 skin lesions 62 were found to be epidermal and dermal adnexal tumours, among these benign adnexal tumours(14%) were the commonest followed by benign epidermal tumours(12.5%) ,malignant epidermal tumours(10.5%) and malignant adnexal tumours(2%).The ratio of benign(42) to malignant(22) tumour was 1.9:1.the ratio of benign(20) to malignant(17) epidermal tumour was 1.17:1 .The ratio of benign adnexal(22) to malignant counterpart (3) was 7.3:1 and the ratio of skin tumours (62) to cystic lesion(98) was 1:1.5. The commonest epidermal tumour was seborrheic keratosis. Epidermal cysts were the commonest type of cyst in the epidermis. Common skin appendage tumours were nodular hidradenoma followed by pilomatrixoma. The common malignant tumour was basal cell carcinoma.
Conclusion: Cutaneous tumours represent the complexity of the epidermal and dermal adnexae since they have a similar morphology to their cell of origin .Hence the histopathological examination is mandatory for diagnosis and categorization of these tumours.
References
Shilpa V, Mandakini T. Histopathological Study of Tumours of Epidermis and Epidermal
Appendages . Indian Journal of Pathology: Research and Practice Volume 6 Number 2,
April - June 2017
Klein W, Chan E, Seykora JT. Tumours of the epidermal appendages. In: Elder DE,
Murphy G . Lever’s histopathology of the skin. 9th ed. Philadelphia. 2005; 867- 926.
Sabir F,Aziz M.Clinical and cyto-histopathological evaluation of skin lesions with special
reference to bullous lesions in Indian journal of pathology and microbiology-
(1),January-march2010.
DeSilva M, Constantine R ,Amarasekara LR. Cutaneous tumours & tumourlike
Conditions and cysts in sri lankans.The Sri Lanka J Dermatol 1999/2004; 21 -27.
.Kapoor R, Goswami KC. Pattern of cancer in Jammu region (Hospital based study 1978-
. Ind J Cancer 1993; 30:67-71.
Shivanand G, Rutuja K. Histopathological Study of Skin Tumours. International Journal of
Healthcare Sciences. Vol. 2, Issue 2, pp: (155-163), Month: October 2014 - March 2015..
.Yoskovitch A, Hier MP, Okrainec A, Black MJ, Rochon L. Skin metastases in squamous
cell carcinoma of the head and neck. Department of Otolaryngology- Head and Neck
Surgery, McGill University, Montreal, Quebec, Canada. Otolaryngol, Head Neck Surg.
Mar;124(3):248-52.
Kirkham N. Tumours and cysts of epidermis. In Lever’s histopathology of skin. 10th ed.
Philadelphia: Lippincott Raven; 2005. p 805-866.
Charkravorthy RC and Choudhuri DR. Malignant neoplasms of the skin in Eastern India.
The Indian Journal of Cancer, vol 5,1968:133-144.
Qiu JH. Pathological studies on epidermic and appendage tumors and tumor- like lesions
analysis of 3,425 cases, Zhonghua Zhong Liu Za Zhi.1986 Jan;8(1):48 .
Reizner GT, Chuang TY, Elpern DJ, Stone JL, Evan RF. Basal cell carcinoma in Kauai,
Hawaii: The highest documented incidence in the United States. J Am Acad Dermatol
;29:184-9.
Tan SH, Tham SN, Goh CL. Skin cancers at tertiary referral skin hospital in Singapore.
Int J Dermatol 1995;34:770-6.
Chuang TY, Popescu A, Chute CG. Basal cell carcinoma: a population Based incidence
study in Rochester, Minnesota. J Am Acad Dermatol 1990;22(3):413-7.
Chandrashekaran CV, Raghuveer CV ,Prakash S. Epidermal cysts – a
clinicopathological and biochemical study. Postgradutate Medical Journal. 1980; 56:
-827.
Chiu MY.Squamous cell carcinoma arising from an epidermal Cyst, Department
of Orthopaedics and Traumatology, Caritas Medical Centre, Hong Kong Med J.
;13:482-4.
Deo SV. Surgical management of skin cancers: Experience from a regional cancer
centre in North India. Indian Journal of Cancer 2005; 42:145-50.
Diepgen TL, Mahler V. The epidemiology of ski cancer. Br Dermatol. 2002
Apr;146 :Suppl 61:1-6.
Sanjay N , Rishi B :Adnexal tumours of skin,Ind J dermatol.43(2)1998.
Yaqoob N Z. Ahmad S. Muzaffar, Gill MS.Spectrum of Cutaneous Appendage
Tumors at Aga Khan University Hospital. Journal of Pakistan Medical Association.
Vol 53 ,No.9,Sep 2003.
.Nair P. A clinicopathologic study of skin appendageal tumors. Indian journal of
Dermatology,Venereology ;2008:550.
Samaila MOA. Adnexal Skin Tumors In Zaria, Nigeria. Annals of African Medicine.
Vol 7, No.1; 2008: 6 – 10.
Solanki A L, Anand V K, Gupta K. Neoplasms of Sweat Glands; Indian J Derematol
Venereal 1989; 55: 108-113.
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