Aspiration Cytology along with Histomorphological correlation of salivary gland lesions

A 5 years retrospective study

Authors

  • Rajini T Sri Devaraj Urs Medical College. Kolar, Karnataka, India.
  • Supreetha Megalamane Sri Devaraj urs Medical College and Research Centre.
  • Subhashish Das Sri Devaraj Urs Medical College. Kolar, Karnataka, India.

DOI:

https://doi.org/10.21276/apalm.2061

Keywords:

Cytology, salivary gland, Histomorphology, cytomorphology

Abstract

Background: Fine needle aspiration cytology (FNAC) of salivary glands is one of the most commonly done first line investigations in the head and neck region. A wide variety of benign and malignant tumors originate in the salivary glands and insufficient tumor cells make their diagnosis difficult in some patients.

The aim of this study was to evaluate the efficacy of fine-needle aspiration cytology in the diagnosis of salivary gland lesions by correlating cytological findings with histopathology.

Methods: All the FNAC slides of salivary gland lesions received at our tertiary hospital for a period of 6years from January 2013 to July 2017were reviewed retrospectively. Histopathological correlation was done for cases wherever available

Result: FNAC categorized 50% of the salivary gland lesions as neoplastic and 50% as non-neoplastic lesions. Amongst the neoplastic lesions, 64.28% were benign and 35.72%were malignant cases. Histopathological examination revealed that 66.64% of the cases were benign and 33.36% were malignant. Fine needle aspiration cytology had a sensitivity, specificity and diagnostic accuracy of 75%, 100% and 94.05%, respectively. The positive predictive value and negative predictive value were 100% and 92.75%, respectively.

Conclusion: : Fine needle aspiration of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. This study has shown that fine needle aspiration cytology has a high sensitivity, specificity and diagnostic accuracy in diagnosing salivary gland lesions. Being an rninimally invasive procedure, FNA of salivary glands continues to be an important diagnostic tool in the preoperative diagnosis of salivary gland lesions despite few pitfalls in diagnosing due to cytomorphological overlapping.

Author Biographies

Rajini T, Sri Devaraj Urs Medical College. Kolar, Karnataka, India.

Department of Pathology

Supreetha Megalamane, Sri Devaraj urs Medical College and Research Centre.

assistant professor. department of pathology

Subhashish Das, Sri Devaraj Urs Medical College. Kolar, Karnataka, India.

Department of Pathology

References

1. Everson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol 1985;46:51-8.
2. Calearo C, Pastore A, Storchi OF, Polli G. Parotid gland carcinoma: analysis of prognostic factors. Ann Otol Rhinol Laryngol 1998;107:969-73.
3. Fulciniti F, Califano L, Zupi A, Vetrani A. Accuracy of fine needle aspiration biopsy in head and neck tumours. J Oral Maxillofac Surg. 1997;55:1094-7.
4. Shaha AR, Webber C, DiMaio T, Jaffe BM. Needle aspiration biopsy in salivary gland lesions. Am J Surg. 1990;160:373-6.
5. Jayaram G, Dashini M. Evaluation of fine needle aspiration cytology of salivary glands: an analysis of 141 cases. Malays J Pathol. 2001;23:93-100.
6. Das DK, Petkar MA, Al-Mane NM, Sheikh ZA, Mallik MK, Anim JT. Role of fine needle aspiration cytology in the diagnosis of swellings in the salivary gland regions: A study of 712 cases. Med Princ Prac 2004;13:95-106.
7. Stramandinoli RT, Sassi LM, Pedruzzi PAG et al. Accuracy, sensitivity and specificity of fine needle aspiration biopsy in salivary gland tumours: A retrospective study. Med Oral Pathol Cir Bucal 2010;15:32-7.
8. Piccioni LO, Fabiano B, Gemma M, Sarandria D, Bussi M. Fine needle aspiration cytology in diagnosis of parotid lesions. Acta Otorhinolarygol Ital. 2011;31:1-4.
9. Iqbal M, Anwar K, Ihsanullah, Mohammad J, Khan IA, Hussain G. The diagnostic value of fine needle aspiration cytology in masses of the salivary glands. JPMI 2011;25: 73-7.
10. Stow N, Veivers D, Poole A. Fine –needle aspiration cytology in the management of salivary gland lesions: an Australian experience. Ear Nose Throat J. 2004;83:128-31.
11. Postema RJ, van Velthuysen MLF, van den Brekel MWM, BalmAJM, Peterse JL. Accuracy of fine needle aspiration cytology of salivary gland lesions in the Netherlands Cancer Institute. Head Neck 2004;26:418-24.
12. Rehman H, Khan MS, Wahid F, Ahmad I. A profile of parotid gland tumours from a tertiary care hospital in Peshawar. JPMI 2011;25:158-62.
13. Lukas J, Duskova J. Fine-needle aspiration biopsy in the diagnosis of tumors and non-neoplastic lesions of salivary glands. Bratisl Lek Listy. 2006;107:12-5.
14. Sahai K, Kapilas K, Dahiya S, Verma K. Fine needle aspiration cytology of minor salivary gland tumours of the palate. Cytopathology 2002;13:309-16.
15. Akhter J, Hirachand S, Lakhey M. Role of FNAC in the diagnosis of salivary gland swellings. KUMJ 2008;6:204-8.
16. Nagarkar N, Bansal S, Dass A, Singhal SK, Mohan H. Salivary gland tumour- our experience. Indian J Otolaryngol Head Neck Surg 2004;56:31-4.
17. Spiro RH. Management of malignant tumours of the salivary glands. Oncol Huntingt 1998;12:671-80.
18. Sengupta S, Roy A, Mallick et al. FNAC of salivary glands. Indian J Otolaryngol Head Neck Surg 2002;54:184-8.
19. Cardillo MR. Salivary gland masses: The diagnostic value of fine needle aspiration cytology. Arch Anat Cytol Pathol 1990;38:26-32.
20. Young JA, Smallman LA, Proops TDW, Johnson AP. Fine needle aspiration cytology of salivary gland lesions. Cytopathology 1990;5:25-33.
21. Stewart CJR, MacKenzie K, McGarry GW, Mowat A. Fine needle aspiration cytology of salivary gland: review of 341 cases. Head Neck 2000;22:139-46.

Downloads

Published

24-11-2018

How to Cite

1.
T R, Megalamane S, Das S. Aspiration Cytology along with Histomorphological correlation of salivary gland lesions: A 5 years retrospective study. Ann of Pathol and Lab Med [Internet]. 2018 Nov. 24 [cited 2024 Nov. 23];5(11):A855-860. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/2061

Issue

Section

Original Article