Cytological diagnosis of Adrenocortical Carcinoma with metastatic lesion in liver
Keywords:
Adrenocortical carcinoma, FNAC, Immunocytochemistry, Liver matastasis,Abstract
Adrenocortical Carcinoma (ACC) is rare tumor with a reported incidence of 2 cases per million individuals per year. These tumors are highly aggressive and at the time of diagnosis, these are at higher stage. Here, we report a case of adrenal mass and multiple hypodense lesions in liver detected on imaging study which on subsequent USG-guided fine needle aspiration cytology (FNAC) performed from adrenal glands and liver turned out to be a ACC with metastatic lesion by using immunocytochemistry as an ancillary technique which showed tumor cells immunoreactivity for inhibin and calretinin; and negativity for cytokeratin, vimentin and epithelial membrane antigen (EMA) thus confirming the suspected morphological diagnosis and highlighting the accuracy of FNAC as a diagnostic tool. Â
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Copyright (c) 2014 Vasudha M Bhagat, Hemali J Tailor, Reena B Dudhat, Ravi M Unjiya
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