A Histomorphological Study of Vesiculobullous Lesions of Skin

Chakor Makarand Rokde; Rajshri P Damle; N V Dravid

doi:10.21276/apalm.2200

Authors

Chakor Makarand Rokde Civil Hospital, Wardha, Maharashtra, India.
Rajshri P Damle Shri Bhausaheb Hire Government Medical College, Dhule, Maharashtra, India
N V Dravid Annasaheb Chudaman Patil Memorial Medical College, Dhule, Maharashtra, India.

DOI:

https://doi.org/10.21276/apalm.2200

Keywords:

Vesiculobullous disorders, Skin biopsies, Histopathological examination

Abstract

Background:
Vesiculobullous disorders are a complex group of disorders which continue to be an enigma. Wide variety of pathological processes can lead to development of Vesiculobullous eruptions over the body. They may occur in many dermatoses which include various inflammatory, infective, autoimmune, drug induced as well as genetic conditions.

Each entity of vesiculobullous lesion has similar or confusing clinical features but different histopathological morphology. Histopathological examination is helpful in definitive diagnosis of vesiculobullous disorder which is very essential for specific treatment and an appropriate desirable outcome.

Aim:
To study and classify various vesiculobullous lesions of the skin in various categories.

Material and Method:
A prospective observational study of vesiculobullous lesions of the skin biopsies of 93 cases were received to the department of pathology over a period of 3 years. Complete clinical and relevant history was recorded. The specimens were routinely processed and haematoxylin and eosin stained slides were studied.

Result:
A total of 93 cases of vesiculobullous lesions of the skin were diagnosed. Among these lesions, Pemphigus vulgaris were seen in 34 (36.55%) cases, Bullous pemphigoid in 22(22.65%) cases of and spongiotic dermatosis in 14 (15.05%) cases. The maximum numbers of cases (32.25%) were in 4^th to 5^th decades.

Conclusion:
Thorough histopathological workup and clinical correlation is essential to confirm diagnosis of vesiculobullous lesions of skin.

Author Biographies

Chakor Makarand Rokde, Civil Hospital, Wardha, Maharashtra, India.

Department of Pathology

Rajshri P Damle, Shri Bhausaheb Hire Government Medical College, Dhule, Maharashtra, India

Department of Pathology

N V Dravid, Annasaheb Chudaman Patil Memorial Medical College, Dhule, Maharashtra, India.

Department of Pathology

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