Chronic Disseminated Histoplasmosis in a Young Immunocompetant Patient of Hypobetalipoproteinemia: A rare Presentation

Authors

  • Rakesh Kumar Gupta G. B. Pant Institute of Post Graduate Medical Education and Research
  • Vineeta Vijay Batra G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi
  • Puja Sakhuja Dept of Pathology, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi
  • Amol Dahale Department of Gastroenterology, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi
  • Amarender Singh Puri Department of Gastroenterology, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi

Keywords:

Histoplasmosis, Immunocompetant, Hypobetalipoproteinemia,

Abstract

Disseminated histoplasmosis is commonly found in immunocompromised patients in association with acquired immunodeficiency syndrome in endemic regions but is rare in other parts of the world. We herein describe a case of subacute disseminated histoplasmosis in a young 20-year-old lady presenting with the chief complaints of pyrexia of unknown origin, loose stools and generalized body swelling with a previous diagnosis of hypobetalipoproteinemia. Supraclavicular lymph node, bone marrow aspiration and colonic biopsy revealed numerous yeast forms of fungus histoplasma. This case illustrates that DH should be ruled out in immunocompetent non-endemic patients presenting with chronic fever even in the absence of respiratory symptoms. 

Author Biographies

Rakesh Kumar Gupta, G. B. Pant Institute of Post Graduate Medical Education and Research

Senior resident Department of Pathology

Vineeta Vijay Batra, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi

Professor, Dept of Pathology, Academic Block, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi

Puja Sakhuja, Dept of Pathology, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi

Professor, Dept of Pathology

Amol Dahale, Department of Gastroenterology, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi

Senior resident, Department of Gastroenterology

Amarender Singh Puri, Department of Gastroenterology, G. B. Pant Institute of Post Graduate Medical Education and Research, New Delhi

Professor, Department of Gastroenterology

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Published

10-05-2015

How to Cite

1.
Gupta RK, Batra VV, Sakhuja P, Dahale A, Puri AS. Chronic Disseminated Histoplasmosis in a Young Immunocompetant Patient of Hypobetalipoproteinemia: A rare Presentation. Ann of Pathol and Lab Med [Internet]. 2015 May 10 [cited 2024 Oct. 30];2(2):C75-79. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/221

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Section

Case Report