Clinico-Pathological Analysis of Thymic Epithelial Tumours
An Institutional Study
DOI:
https://doi.org/10.21276/apalm.2341Keywords:
Anterior mediastinum, Thymic epithelial tumours, Myasthenia gravis, Masaoka stagingAbstract
Background:
Thymic epithelial tumours are anterior mediastinal neoplasms and they exhibit a spectrum of histomorphological features.
Methods:
In this study we analysed the clinico-pathological spectrum of thymic epithelial tumors at our institution. It is a retrospective and descriptive study done at our Department of Pathology, Amala Institute of Medical Sciences, Thrissur, Kerala over a period of ten years from August 2008 to August 2018. Histological sections of each case were meticulously analysed. Immunohistochemistry was done if needed.
Result:
In this study 17 cases of thymic epithelial tumors were analysed. A male preponderance of 58.8% was observed. Age ranged from 24 to 73 years with a mean age range of 54.4 years. Most common histological subtype of thymoma was Type B and Type AB. 4 cases were associated with myasthenia gravis. Masaoka Stage I was commonly observed.
Conclusion:
Thymic epithelial tumors are a unique group of anterior mediastinal neoplasms which also pose a diagnostic challenge. This study highlights the significance of clinico-pathological correlation and staging of thymic neoplasms.
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Copyright (c) 2018 Divya S, Sreeja Raju, Joy Augustine, Ajay Kumar
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