Acquired Coagulopathies Secondary to Plasma Cell Dyscrasias
A Report of Two Cases and Review of Literature
DOI:
https://doi.org/10.21276/apalm.2398Keywords:
Bleeding, dysfunction, hemostatic, paraproteinemias, plasma cell dyscraciasAbstract
We report hemostatic dysfunction in two postmenopausal women presenting with mucosal bleeds secondary to plasma cell dyscrasias. The two postmenopausal women presented with complaints of mucosal bleeds like gum bleed and epistaxis. Peripheral smear examination showed rouleaux formation. After detailed haematological and coagulation work up, one patient was diagnosed as Waldenstro¨m macroglobulinemia (WM) with acquired vWD and impaired platelet function. The second patient was diagnosed as Multiple myeloma (MM) with acquired coagulopathy. Evaluation of elderly patients with bleeding manifestations should also include work up ruling out an acquired coagulation abnormality secondary to plasma cell dyscracia.
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Copyright (c) 2019 Hitha Diljith, Ambika Lokababu Pagadalu, Sreerekha Jinkala, Rakhee Kar, Sajini Elizabeth Jacob, Debdatta Basu
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