Lesions of the Eyelid: A 5 - year Retrospective Study in a Tertiary Care Centre
Keywords:
Benign, eyelid lesions, malignant, sebaceousAbstract
Background: Eyelid oncology is of utmost importance. Eyelid lesions are rarely lethal and completely treatable if detected early. Overview of eyelid lesions guides ophthalmogists to design for optimal therapy.
Materials and methods: A retrospective analysis of eyelid lesion was done from 2013 to 2018 in the department of pathology, VSSIMSAR, Burla, Odisha, confirmed through histopathology. Data regarding age, sex and topography of lesion were also included.
Results: A total of 104 biopsies were evaluated. Male to female ratio were 1:1.16 for benign tumours and 1:1.36 for malignant tumours. The age of the patient at the time of biopsies ranged from ½ year to 78 years old. The most common benign eyelid lesion encountered in our practice was epidermoid cyst followed by vascular haemangioma.
Conclusion: The majority of eyelid lesions were benign eyelid tumours while malignant eyelid tumours contributed 25% of total eyelid lesions. Sebaceous gland carcinoma was the most common eyelid tumour found in the present study that was consistent with other studies for Asian countries.
References
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26. Abe MY, Ohnishi Y, Hara Y, Shinoda Y, Jingu K. Malignant tumor of the eyelid-Clinical survey during 22-year period. Jpn J Ophthalmol. 1983; 27:175–84.
27. Suresh Saquil, Raman Malhotra.The importance of considering Sebaceous gland carcinoma in presumed chalazian in South Asian patients.Br J Gen Pract.Feb 2013; 63 (607): 74.
2. Lee SB, Saw SM, Eong KGA, Chan TK, Lee HP. Incidence of eyelid cancers in Sin-gapore from 1968 to 1995.Br J Ophthalmol.1999; 83: 595–597.
3. Mihaela-Cristiana Coroi, Elena Rosca, Gabriela Mutiu, T.Coroi, Marinela Bonta. Eyelid tumors: histopathological and clinical study performed in County Hospital of Oradea between 2000 - 2007. Romanian Journal of Morphology and Embryology 2010; 51(1):111-115.
4. Lin HY, Cheng CY, Hsu WM, Kao WH, Chou P. Incidence of eyelid cancers in Taiwan: A 21-year review. Ophthalmology. 2006; 113:2101–7.
5. Abdi UN, Tyagi V, Maheshwari V, Gogi R, Tyagi SP. Tumors of eyelid: A clinicopathologic study. J Indian Med Assoc. 1996; 94(11):405–9, 416, 418.
6. Zimmerman LE, LH Sabin. Histological typing of tumours and its adnexa. Class Int Tumours 1980; Geneva 24:46.
7. Obata H, Aoki Y, Kubota S, Kanai N, Tsuru T, Incidence of benign and malignant lesions of eyelid and conjunctival tumors. Nippon Ganka Gakkai Zasshi 2005 Sep; 109(9):573-9.
8. Paul S, Vo DT, Silkiss RZ. Malignant and benign eyelid lesions in San Francisco: study of a diverse urban population. Am J Clin Med. 2011; 8(1):40–46.
9. Huang YY, Liang WY, Tsai CC, Kao SC, Yu WK, Kau HC, Liu CJL. Comparison of the clinical characteristics and outcome of Benign and Malignant Eyelid Tumors: An analysis of 4521 Eyelid tumors in a Tertiary Medical Centre. Bio Med Research International.2015;2015:453091.
10. Sushma, TA, Geethamani V, Thejaswini MU, Suguna BV, & Dharani VC Epidemiology of neoplastic eyelid lesions in tertiary care hospital. Indian Journal of Pathology and Oncology. 2018;5(1):67-74
11. Krishnamurthy H, Tanushree V, Venkategowda H. T, Archana S, Mobin G, Aylette D Silva, Bharathi M, Savita Patil; profile of eyelid tumours at tertiary care institute in Karnataka: a 5-years survey. JEMDS, 2014: vol. 3, issue 50; 11818-11832.
12. Ramya BS, Dayananda SB, Chinmayee JT, Raghupathi AR. Tumours of the eyelid-A Histopathological Study of 86 cases in a Tertiary Hospital. International Journal of Scientific and Research Publications, 2014; 4(11):1-5.
13. Jangir MK, Kochar A, Khan NA, Jaju M. Profile of eyelid tumours: histopathological examination and relative frequency at a tertiary centre in north-west Rajasthan. Delhi J Ophthalmol. 2017; 28(2): 30–5
14. Rathod A, Pandharpukar M, Toopalli K, Bele S. A clinicopathological study of eyelid tumors and its management at a tertiary eye care centre of Southern India. MRIMS J Health Sci. 2015; 3(1):54-58.
15. Ho Mary, Liu David TL, Chong Kelvin KL, Ng HK, Lam Dennis SC. Eyelid tumours and pseudotumours in Hong Kong: a ten -year experience. Hong Kong Med Journal 2013;19:150-155.
16. Kale SM, Patil SB, Khare N, Math M, Jain A, Jaiswal S. Clinicopathological analysis of eyelid malignancies-A review of 85 cases. Indian J Plast Surg 2012; 45(1):22-28.
17. Pornpanich K, Chindasub P. Eyelid tumors in Siriraj Hospital from 2000-2004. J Med Assoc Thai.2005; 88:S11–14.
18. Satyanarayana C. Rhinosporidiosis with a record of 255 cases. Acta Otolaryngologica.1960; 5:348-66.
19. Averbuch D,Jaouni T,Pe'er J,Engelhard D.Confluent molluscum contagiosum covering the eyelids of an HIV –positive child. Clin Experiment Opthalmol.2009; 37:525-527.
20. Llamas-Velasco M, Eguren C, Santiago D, et al. Calcinosis cutis and Sjogren's syndrome. Lupus 2010;19:762-4
21. Bastola P, Koirala S, Pokhrel G, Ghimire P, Adhikari RK, A clinico-histopathological study of orbital and ocular lesions: A multicenter study. Journal of Chitwan Medical College. 2013; 3(4):40-44.
22. Kaliki S, Bothra N, Bejjanki K, M, Nayak A, Ramappa G, Mohamed A, Dave T, V, Ali M, J, Naik M, N: Malignant Eyelid Tumors in India: A Study of 536 Asian Indian Patients. Ocul Oncol Pathol 2019;5:210–219
23. Cook BE, Jr, Bartley GB. Epidemiologic characteristics and clinical course of patients with malignant eyelid tumors in an incidence cohort in Olmsted county, Minnesota. Ophthalmology. 1999; 106:746–50.
24. Yu SS, Zhao Y, Zhao H, Lin JY, Tang X. A retrospective study of 2228 cases with eyelid tumors. Int J Ophthalmol. 2018; 11(11):1835-1841.
25. Chang-Jun Wang, Hui-Na Zhang, Han Wu, Xin Shi, Jia-Jun Xie, Jin-Jing He, Koung-Hoon KooK, Sang-Yeul Lee and Juan Ye. Clinicopathologic features and prognostic factors of malignant eyelid tumors. Int J Ophthalmol. 2013; 6(4): 442–447. Published online Aug 18, 2013.
26. Abe MY, Ohnishi Y, Hara Y, Shinoda Y, Jingu K. Malignant tumor of the eyelid-Clinical survey during 22-year period. Jpn J Ophthalmol. 1983; 27:175–84.
27. Suresh Saquil, Raman Malhotra.The importance of considering Sebaceous gland carcinoma in presumed chalazian in South Asian patients.Br J Gen Pract.Feb 2013; 63 (607): 74.
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01-08-2019
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Toppo A, Sahu A, Pradhan I, Agrawal KC. Lesions of the Eyelid: A 5 - year Retrospective Study in a Tertiary Care Centre. Ann of Pathol and Lab Med [Internet]. 2019 Aug. 1 [cited 2024 Dec. 22];6(7):A359-365. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/2543
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Copyright (c) 2019 Anupa Toppo, Alaka Sahu, Ipsita Pradhan, Kailash Chandra Agrawal
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