Cytomorphology of Chondroid Syringoma: Analysis of 20 Cases and Review of Literature
DOI:
https://doi.org/10.21276/apalm.2592Keywords:
Chondroid syringoma, Skin adnexal tumors, Cytomorphological variation, ChondromyxoidAbstract
Background: Chondroid syringomas [CS] are interesting skin adnexal tumours. They have a remarkable pleomorphic-adenoma like morphology in the skin. Though the histopathology of the tumour has been described in detail in literature, cytomorphological studies are restricted to case reports and small case series. For diagnosing a CS on cytology, the index of suspicion must be high, clinical evaluation must be thorough and knowledge of variant existing morphologies is essential.
Aim: This study was done with the aim of studying the common and variant cytological features of chondroid syringomas.
Methods: This was a retrospective study conducted over a four-year period (2014-17) in the Department of Pathology, VMMC and Safdarjung hospital. Fine needle aspirate smears and biopsy slides were studied. Morphological details were independently reviewed in detail by two pathologists (Dr MS and Dr MA).
Result and Conclusion: The conventional biphasic cell morphology of CS was seen in nearly 50% cases. Rest of the cases showed predominance of one or more variant features in few areas and thus CS was only one of the differential diagnosis in these cases. Nevertheless, FNA proved to be fast, inexpensive and a reliable method for diagnosis of chondroid syringoma. The study will be relevant and helpful in the day to day cytological reporting of CS.
References
2. Kundu R, Punia RS, Handa U, et al. Chondroid syringoma: Cytomorphology of four cases and review of literature. Archives of Cytology and Histopathology Research. 2016;1:63-7.
3. Harrist TJ, Aretz TH, Mihm MC Jr, et al. Malignant chondroid syringoma. Arch Dermatol. 1981;117:719-24.
4. Hirsch P, Helwig EB. Chondroid syringoma: Mixed tumour of skin, salivary gland type. Arch Dermatol. 1961;84:835-47.
5. Yavuzer R, Basterzi Y, Sari A, et al. Chondroid syringoma: a diagnosis more frequent than expected. Dermatol Surg. 2003;29:179-81.
6. Silvanto AM, Melly L, Hannan SA, et al. FNAC of nodular fasciitis mimicking a pleomorphic adenoma: another diagnostic pitfall. Cytopathology. 2010;21:276-7.
7. Moon A, Chin S, Kim HK, et al. Myoepithelioma of soft tissue in the knee: A case report of an unusual location. Indian J Pathol Microbiol. 2016;59:254-6.
8. Khan K. Chondroid syringoma: a case with unusual cytological findings. Indian J Dermatol. 2013;58:157.
9. Headington JT. Mixed tumours of skin: eccrine and apocrine types. Arch Dermatol. 1961;84:989-96.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Meetu Agrawal, Mukul Singh, Rituraj ., Sachin Kolte, C Ahluwalia, Neha Madan, Rasmi Aurora
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).