Cytomorphology of Chondroid Syringoma: Analysis of 20 Cases and Review of Literature

Authors

  • Meetu Agrawal Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Mukul Singh Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Rituraj . Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Sachin Kolte Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • C Ahluwalia Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Neha Madan Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029
  • Rasmi Aurora Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

DOI:

https://doi.org/10.21276/apalm.2592

Keywords:

Chondroid syringoma, Skin adnexal tumors, Cytomorphological variation, Chondromyxoid

Abstract

Background: Chondroid syringomas [CS] are interesting skin adnexal tumours. They have a remarkable pleomorphic-adenoma like morphology in the skin. Though the histopathology of the tumour has been described in detail in literature, cytomorphological studies are restricted to case reports and small case series. For diagnosing a CS on cytology, the index of suspicion must be high, clinical evaluation must be thorough and knowledge of variant existing morphologies is essential.

Aim: This study was done with the aim of studying the common and variant cytological features of chondroid syringomas.

Methods: This was a retrospective study conducted over a four-year period (2014-17) in the Department of Pathology, VMMC and Safdarjung hospital. Fine needle aspirate smears and biopsy slides were studied. Morphological details were independently reviewed in detail by two pathologists (Dr MS and Dr MA).

Result and Conclusion: The conventional biphasic cell morphology of CS was seen in nearly 50% cases. Rest of the cases showed predominance of one or more variant features in few areas and thus CS was only one of the differential diagnosis in these cases. Nevertheless, FNA proved to be fast, inexpensive and a reliable method for diagnosis of chondroid syringoma. The study will be relevant and helpful in the day to day cytological reporting of CS.

Author Biographies

Meetu Agrawal, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

Department of Pathology

Mukul Singh, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

Department of Pathology

Rituraj ., Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

Department of Pathology

Sachin Kolte, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

Department of Pathology

C Ahluwalia, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

Department of Pathology

Neha Madan, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

Department of Pathology

Rasmi Aurora, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital (SJH), New Delhi. India 110029

Department of Pathology

References

1. Lamba S, Nanda A, Kumar U. Chondroid Syringoma: Fine-needle Aspiration Cytology of a Rare Entity at an Unusual Site. Journal of Clinical and Diagnostic Research. 2017;11:ED06-ED07.
2. Kundu R, Punia RS, Handa U, et al. Chondroid syringoma: Cytomorphology of four cases and review of literature. Archives of Cytology and Histopathology Research. 2016;1:63-7.
3. Harrist TJ, Aretz TH, Mihm MC Jr, et al. Malignant chondroid syringoma. Arch Dermatol. 1981;117:719-24.
4. Hirsch P, Helwig EB. Chondroid syringoma: Mixed tumour of skin, salivary gland type. Arch Dermatol. 1961;84:835-47.
5. Yavuzer R, Basterzi Y, Sari A, et al. Chondroid syringoma: a diagnosis more frequent than expected. Dermatol Surg. 2003;29:179-81.
6. Silvanto AM, Melly L, Hannan SA, et al. FNAC of nodular fasciitis mimicking a pleomorphic adenoma: another diagnostic pitfall. Cytopathology. 2010;21:276-7.
7. Moon A, Chin S, Kim HK, et al. Myoepithelioma of soft tissue in the knee: A case report of an unusual location. Indian J Pathol Microbiol. 2016;59:254-6.
8. Khan K. Chondroid syringoma: a case with unusual cytological findings. Indian J Dermatol. 2013;58:157.
9. Headington JT. Mixed tumours of skin: eccrine and apocrine types. Arch Dermatol. 1961;84:989-96.

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Published

01-12-2019

How to Cite

1.
Agrawal M, Singh M, . R, Kolte S, Ahluwalia C, Madan N, et al. Cytomorphology of Chondroid Syringoma: Analysis of 20 Cases and Review of Literature. Ann of Pathol and Lab Med [Internet]. 2019 Dec. 1 [cited 2024 Oct. 30];6(11):A605-610. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/2592

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Original Article