Incidental Prostate Carcinoma Diagnosed at Radical Cystoprostatectomy for Bladder Carcinoma

A Case Report

Authors

  • Sonal Paul Lokmanya Tilak Medical college and General Hospital, Sion, Mumbai, India
  • Anitha Padmanabhan Lokmanya Tilak Medical college and General Hospital, Sion, Mumbai, India
  • Nitin M Gadgil Lokmanya Tilak Medical college and General Hospital, Sion, Mumbai, India

DOI:

https://doi.org/10.21276/apalm.2687

Keywords:

Carcinoma prostate, Cystoprostatectomy, Incidental, Urothelial carcinoma bladder

Abstract

Introduction: The incidence of concomitant urothelial carcinoma of the bladder and adenocarcinoma of the prostate varies from 17% to 70% as per various literature studies.

Case report: We report the case of 82 year old male who presented with hematuria and lower urinary tract symptoms. A cystoscopy was performed which was suggestive of a 6x4x5cm mass arising from the left anterolateral wall and dome of the bladder. A Transurethral biopsy of the bladder mass showed a high grade papillary urothelial carcinoma invading the muscularis propria. Following this, the patient underwent a radical cystoprostatectomy. Histopathological examination of the bladder mass confirmed High -grade urothelial carcinoma. The entire prostate was sampled which revealed Adenocarcinoma prostate, Gleason score 3+4=7, tumor volume 6cc.

Conclusion: The incidence of incidentally detected prostatic adenocarcinoma in Carcinoma bladder cases is extremely variable. Complete sampling of the prostate helps in detecting these lesions.

Author Biographies

Sonal Paul, Lokmanya Tilak Medical college and General Hospital, Sion, Mumbai, India

Department of Pathology

Anitha Padmanabhan, Lokmanya Tilak Medical college and General Hospital, Sion, Mumbai, India

Department of Pathology

Nitin M Gadgil, Lokmanya Tilak Medical college and General Hospital, Sion, Mumbai, India

Department of Pathology

References

1.Damiano R, Lorenzo GD, Cantiello F et al. Clinicopathologic features of prostate adenocarcinoma incidentally discovered at the time of radical cystectomy: an evidence based analysis. Eur Urol 2007;52:648-57.
2.Heidegger I, Oberaigner W, Horninger W, Pichler R. High incidence of clinically significant concomitant prostate cancer in patients undergoing radical cystectomy for bladder cancer: a 10-year single center experience. Urol Oncol 2017;35:152e1-e5.
3. Saad M, Abdel-Rahim M, Abol-Enein H, Ghoneim MA. Concomitant pathology in the prostate in cystoprostatectomy specimens: a prospective study and review. BJU Int 2008;102:1544-50.
4.Kaelberer JB, O'Donnel MA, Mitchell DL et al. Incidental prostate cancer diagnosed at radical cystoprostatectomy for bladder cancer: disease specific outcomes and survival. Prostate Int 2016;4:107-12.
5.Autorino R, Lorenzo GD, Damiano R et al. Pathology of prostate in radical cystectomy specimens: a critical review. Surg. Oncol. 2009;18:73-84.
6. Tanaka T, Koie T, Ohyama C et al. Incidental prostate cancer in patients with muscle-invasive bladder cancer who underwent radical cystoprostatectomy. Jpn J Clin Oncol. 2017;47:1078-1082.
7. Pan J, Xue W, Sha J et al. Incidental Prostate Cancer at the Time of Cystectomy: The Incidence and Clinicopathological Features in Chinese Patients. PLoS One. 2014;9(4):e94490.
8. Mahadik R, Bijalwan P, Thomas A. Prevalence and Pathological Analysis of Adenocarcinoma Prostate Discovered Incidentally in Radical Cystoprostatectomy Specimen: An Indian Center Experience. Journal of Clinical and Diagnostic Research. 2018;12:XC01-XC03.

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Published

12-03-2020

How to Cite

1.
Paul S, Padmanabhan A, Gadgil NM. Incidental Prostate Carcinoma Diagnosed at Radical Cystoprostatectomy for Bladder Carcinoma: A Case Report. Ann of Pathol and Lab Med [Internet]. 2020 Mar. 12 [cited 2024 Nov. 24];7(2):C31-34. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/2687

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Section

Case Report