Rare Neurogenic Tumor - Pacinian Neurofibroma

A Case Report

Authors

  • Shivani Panhotra Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India
  • Zeeba S Jairajpuri Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India
  • Beenish Sultan Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India
  • Sujata Jetley Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India
  • Nehal Ahmad Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India

DOI:

https://doi.org/10.21276/apalm.2693

Keywords:

Pacinian neurofibroma, Pacinian corpuscles, S-100 antibodies

Abstract

Pacinian neurofibroma (PN), a rare benign dermal tumor characterized by proliferation of pacinian corpuscles in the dermal myxoid stroma. A 50 year female presented with slow growing, soft, painless swelling over right wrist. No other significant history was found. Histopathology revealed proliferation of fibrous connective tissue along with whorled structures. No cellular atypia was found. Immunohistochemistry examination with antibodies against protein S-100 showed diffuse positivity. A diagnosis of Pacinian neurofibroma was made.

Author Biographies

Shivani Panhotra, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India

Department of Pathology

Zeeba S Jairajpuri, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India

Department of Pathology

Beenish Sultan, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India

Department of Pathology

Sujata Jetley, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India

Department of Pathology

Nehal Ahmad, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi 110062, India

Department of Pathology

References

1. Deshpande GU, Bhatoe HS, Ramji Rai, NK Panicker. Pacinian neurofibroma of the scalp. Med J Armed Forces India.1997;53(2):135-36.
2. Nath AK, Timshina DK, Thappa DM, Basu D. Pacinian neurofibroma: a rare neurogenic tumor. Indian J Dermatol Venereol Leprol.2011;7:204-5.
3. Bennin B, Barsky S, Salgia K. Pacinian neurofibroma. Arch Dermatol 1976;112:1558.
4. HH Cho, JS Hong, SY Park, HS Park, S Cho, JH Lee. Tender Papule Rising on the Digit: Pacinian Neuroma Should Be Considered in Differential Diagnosis. Int J Med Sci. 2012; 9(1): 83–85.
5. Idler RS. Benign and malignant nerve tumors. Hand Clin 1995;11:203-209.
6. Fletcher CDM, Theaker JM. Digital pacinian neuroma: a distinctive hyperplastic lesion. Histopathology 1989;15:249–256.
7. McCormack K, Kaplan D, Murray JC, Fetter BF. Multiple hairy pacinian neurofibromas (nerve-sheath myxomas). J Am Acad Dermatol 1988;18:416-9.
8. Levi L, Curri SB. Multiple Pacinian neurofibroma and relationship with the finger-tip arterio-venous anastomoses. Br J Dermatol 1980;102:345-9.
9. MacLennan SE, Aldana HM, Yakuboff KP. Pacinian Neurofibroma of the Hand: A Case Report and Literature Review. J Hand Surg 1999; 24A:413-16.

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Published

12-03-2020

How to Cite

1.
Panhotra S, Jairajpuri ZS, Sultan B, Jetley S, Ahmad N. Rare Neurogenic Tumor - Pacinian Neurofibroma: A Case Report. Ann of Pathol and Lab Med [Internet]. 2020 Mar. 12 [cited 2024 Dec. 26];7(2):C35-37. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/2693

Issue

Vol. 7 No. 2 (2020)

Section

Case Report

License

Copyright (c) 2020 Shivani Panhotra, Zeeba S Jairajpuri, Beenish Sultan, Sujata Jetley, Nehal Ahmad

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