Rare Neurogenic Tumor - Pacinian Neurofibroma
A Case Report
DOI:
https://doi.org/10.21276/apalm.2693Keywords:
Pacinian neurofibroma, Pacinian corpuscles, S-100 antibodiesAbstract
Pacinian neurofibroma (PN), a rare benign dermal tumor characterized by proliferation of pacinian corpuscles in the dermal myxoid stroma. A 50 year female presented with slow growing, soft, painless swelling over right wrist. No other significant history was found. Histopathology revealed proliferation of fibrous connective tissue along with whorled structures. No cellular atypia was found. Immunohistochemistry examination with antibodies against protein S-100 showed diffuse positivity. A diagnosis of Pacinian neurofibroma was made.
References
2. Nath AK, Timshina DK, Thappa DM, Basu D. Pacinian neurofibroma: a rare neurogenic tumor. Indian J Dermatol Venereol Leprol.2011;7:204-5.
3. Bennin B, Barsky S, Salgia K. Pacinian neurofibroma. Arch Dermatol 1976;112:1558.
4. HH Cho, JS Hong, SY Park, HS Park, S Cho, JH Lee. Tender Papule Rising on the Digit: Pacinian Neuroma Should Be Considered in Differential Diagnosis. Int J Med Sci. 2012; 9(1): 83–85.
5. Idler RS. Benign and malignant nerve tumors. Hand Clin 1995;11:203-209.
6. Fletcher CDM, Theaker JM. Digital pacinian neuroma: a distinctive hyperplastic lesion. Histopathology 1989;15:249–256.
7. McCormack K, Kaplan D, Murray JC, Fetter BF. Multiple hairy pacinian neurofibromas (nerve-sheath myxomas). J Am Acad Dermatol 1988;18:416-9.
8. Levi L, Curri SB. Multiple Pacinian neurofibroma and relationship with the finger-tip arterio-venous anastomoses. Br J Dermatol 1980;102:345-9.
9. MacLennan SE, Aldana HM, Yakuboff KP. Pacinian Neurofibroma of the Hand: A Case Report and Literature Review. J Hand Surg 1999; 24A:413-16.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Shivani Panhotra, Zeeba S Jairajpuri, Beenish Sultan, Sujata Jetley, Nehal Ahmad
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).