Primary Thyroid Lymphoma
A Rare Case Report
DOI:
https://doi.org/10.21276/apalm.2735Keywords:
Primary Thyroid Lymphoma, Hashimoto’s Thyroiditis, B Cell Lymphoma, ImmunohistochemistryAbstract
Primary thyroid lymphoma (PTL) is a rare condition and accounts for 5% of all thyroid malignancies. They constitute less than 2 % of all lymphomas. Most PTL’s are non-Hodgkin's lymphomas. It is clinically essential to discriminate between primary or secondary lymphoma of the thyroid as the treatment and prognosis varies. It commonly occurs in women in their sixth and seventh decade. Primary thyroid lymphoma is quite curable without the need for extensive surgery if diagnosed early. We present such a case of a 60- year old female patient presenting with complaints of neck swelling with loss of appetite and dysphagia. Histopathological diagnosis confirmed Primary thyroid lymphoma of B cell origin which was confirmed by immunohistochemistry.
References
2. Chen C et al., Primary thyroid T-lymphoblastic lymphoma: a case report and
review of the literature, Int. J. Clin. Exp. Pathol.2014;7 (1):443-450.
3. Takashima S, et al., Secondary malignant lymphoma which simulated primary
thyroid cancer, J. Clin. Imaging.2000;24:162-165.
4. Graff-Baker, J.A. Sosa, Roman S.A, Primary thyroid lymphoma: a review of
recent developments in diagnosis and histology-driven treatment, Curr. Opin.Oncol. 2010;22:17–22.
5. Sakorafas G.H., Kokkoris P, Farley D.R., Primary thyroid lymphoma - diagnostic and therapeutic dilemmas, Surg. Oncol.2010;19:e124-e129.
6. Widder S, Pasieka J.L, Primary thyroid lymphomas, Curr. Treat. Options Oncol.
2004;5 (4) :307-313.
7. Mo shynska OV, Saxena A. Clonal relationship between Hashimoto thyroiditis and thyroid lymphoma. J Clin Pathol 2008;61: 438-444
8. Teixeira Mendes L.S, Wotherspoon A, Marginal zone lymphoma: associated
autoimmunity and auto-immune disorders, Best Pract. Res. Clin. Haematol.2016;1-12
9. Katna R, Shet T, Sengar M, et al., Clinicopathologic study and outcome analysis of thyroid lymphomas: experience from a tertiary cancer center,Head Neck 2013; 35:165-171.
10. Derringer G.A, Thompson L.D, Frommelt R.A al., Malignant lymphoma of the thyroid gland: a clinicopathologic study of 108 cases, Am. J. Surg. Pathol.2000;24:623-639.
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Copyright (c) 2020 Sripriya Krishnan, I V Renuka, C H Ramya, Harshitha .
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