Histomorphological Spectrum of Renal diseases: A Prospective Study for A Period of Two Years
DOI:
https://doi.org/10.21276/apalm.2785Keywords:
Chronic pyelonephritis, Renal cell carcinoma, malignant tumorAbstract
INTRODUCTION: Kidneys are vital organs of the body with multiple functions like excretory, acid base balance and maintenance of blood pressure. Renal parenchyma is mostly subjected to noxious insults but is last to respond. Simple nephrectomy is done for irreversibly damaged kidney. Most common indication for nephrectomy is chronic pyelonephritis. Aim of the study is to analyze the histopathological patterns of renal lesions and to analyze age and sex distribution.
MATERIALS AND METHODS: The study included a total number of 70 cases, during a period of 2 years i.e., from October 2017 to September 2019. All renal biopsies and nephrectomy specimens received in pathology department, SVS Medical College, Mahabubnagar, Telangana, India were included in the study.
RESULTS: In our study, 70 cases were analyzed. Out of which majority of the lesions (25.7 % ) were in the age group of 21-40 years and showed male preponderance (68.5 %). Present study showed chronic pyelonephritis being the most common non-neoplastic lesion. Among malignant tumors renal cell carcinoma was most common.
CONCLUSION: The present study reveals various histological patterns of lesions in renal biopsies and nephrectomy specimens. Our study reveals that non-neoplastic lesions are more commonly encountered lesions.
References
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27. Tabibi A, Parvin M, Abdi H, Bashtar R, Zamani N. Correlation between size of renal cell carcinoma and its grade, stage and histological subtype. Urol J. 2008; 4: 10-13.
28. Fuhrman SA, Lasky LC, Limas C. Prognostic Significance of Morphological parameters in renal cell carcinoma. Am J Surg Path. 1982; 6: 655-63.
29. Srivastava A, Mandhani A, Kapoor R, Jain M, Dubey D, Raghavendra MA et al. Prognostic factors in patients with renal cell carcinoma: Is TNM (1997) staging relevant in Indian subpopulation. Indian J Cancer. 2004; 41:99-103
30. Jha MS, Gupta N, Agrawal S, Ansari MS, Dubey D Mandhani A et al. Single centre experience of laproscopic nephrectomy: impact of learning curve on outcome. Indian J Urol. 2007;23 (3):253-56
31. Bharti DT, Kailash S (2017) A histopathological review of Nephrectomy specimens Received in a Tertiary care hospital-A retrospective study. J Med Sci Cl Res 5(6): 23807-23810.
32. Davenport K, Temoney AG, Reeley FX: A 3 year review of British association of urological surgeons sections of endourology laproscopic nephrectomy audit. BJ U Int. 2005; 97: 333-37.
33. Ashima NA, Pushpalatha P, Krishnaraj U (2015) A Histopathological spectrum of nephrectomy specimens in a tertiary hospital in southern India. Int J Biol Med Research. 6(3): 5173-5178.
34. Beisland C, Medley PC, Sander S. Nephrectomy indications complications and postoperative mortality in 646 consecutive patients. Eur Urol. 2000; 37: 58-64.
35. Mannan R, Kaur H, Singh PA et al. A Histopathological spectrum of Renal lesions : A 3 year prospective study of a Tertiary care teaching centre. Int J Dent Med Res 2015;1(6): 11-13.
2. Monalisa H et al. Histopathological spectrum of pediatric nephrectomies. Indian Journal of Pathology and Microbiology, 2010; 53(1):101-102.
3. Vinay KS, Sujatha S. Histopathological Spectrum of Nephrectomy Specimens: Single Center Experience. Biomed J Sci&Tech Res 6(3)- 2018. BJSTR. MS.ID.001350.
4. Aiman A, Singh K, Yasir M. Histopathological spectrum of lesions in nephrectomy specimens: A five-year experience in a tertiary care hospital. J SciSoc 2013;40:148-54.
5. Shanmugasamy K, Anandrajvaithy, Venkatraman K, Dhananjay S Kotasthane. Histopathological spectrum of nephrectomy specimen in a tertiary care centre: with an emphasis on chronic pyelonephritis. Ann Path Lab Med 2017;4(5): 573-578.
6. Ray R, Mahapatra R, Khullar S, Pal D, Kundu A. Clinical characteristics of renal cell carcinoma: Five years review from a tertiary hospital in Eastern India. Indian J Cancer. 2016;53(1):114-17.
7. Muhammad A, Khan K, Rana S. Nephrectomy- an overview, Pak J Surj,2012, 28(2):102-105.
8. Kishor H. Suryawanshi1, Rajshri P. Damle - Annals of Pathology and Laboratory Medicine, 2017; 4,
9. Swarnlatha A, Rohit A. Histopathological spectrum of lesions in nephrectomies- A five year study. Int J Sci Res 2017;6(7): 44-46.
10. Ajay K. A histopathological study of non neoplastic lesions in nephrectomy specimens. Int J Med H Res 2017: 3(2): 137-138.
11. Reddy KD, Gollapalli SL, Chougani S, Shivalalitha Sidagam, Amanulla khan Mohmmed, et al. A clinic-morphological spectrum of nephrectomy specimens-an experience from a tertiary care hospital. Int J Health Sci Res 2016;6(11): 67-72.
12. Islam SJ, Haque WS, Akhter S, Mahbubul Alam S M. Histomorphological pattern of renal biopsy in Dhaka: A single center study. Saudi J Kidney Dis Transpl 2018;29:1159-64
13. Mohammad N, Khan TM, Orakzai AN, Imran M. Histological pattern of glomerulopathies. Gomal J Med Sci 2012;10:7-11.
14. Habib MA, Badruddoza SM. Pattern of glomerular diseases among adults in Rajshahi, the Northern region of Bangladesh. Saudi J Kidney Dis Transpl 2012;23:876-80.
15. Beniwal P, Singh SK, Malhotra V, Agarwal D, Sharma M, Joshi P, Khandelwal S, Gaur N, Sharma S. Gerontolizing nephrology: Spectrum of histopathological findings of kidney biopsy in the elderly. Indian J Nephrol[Ahead of print publication].
16. Kohli HS, Jairam A, Bhat A, Sud K, Jha V, Gupta KL, et al. Safety of kidney biopsy in elderly: A prospective study. Int Urol Nephrol 2006;38:815-20.
17. Narang VI, Garg BH, Walia AS, Sood NE, Malhotra VI. Histomorphological Spectrum of Nephrectomy Specimens-A Tertairy Care Centre Experience. National Journal of Laboratory Medicine. 2016 Apr;5(2):51-4.
18. Ghalyini IF. Pathological spectrum of nephrectomies in a general hospital. Asian J Surg. 2002;25 (2):163-69.
19. Nggada HA, Eni UE, Nwankuro EA. Histopathological finding in nephrectomy specimens. A review of 42 cases. Niger Postgrad Med. J. 2006; 13(3):244-46.
20. Eke N, Echen RC, Nephrectomy at the university of part Harconsist Teaching Hospital; a ten year experience. Afer J Med Sci. 2003; 32(2):173-77.
21. Jalalah SM. Patterns of primary glomerular diseases among adults in the western region of Saudi Arabia. Saudi J Kidney Dis Transpl 2009;20:295-9.
22. Mardanpour K, Rahbar M. Histopathologic patterns of adult renal disease in Kermanshah, Iran: A 6-year review of two referral centers. Caspian J Intern Med 2013;4:717-21.
23. Balakrishnan N, John GT, Korula A. Spectrum of biopsy proven renal disease and changing trends at a tropical tertiary care centre 1990-2001. Indian J Nephrol 2003;13:29-35.
24. Li LS, Liu ZH. Epidemiologic data of renal diseases from a single unit in China: Analysis based on 13,519 renal biopsies. Kidney Int 2004;66:920-3.
25. Mubarak M, Kazi JI, Naqvi R, et al. Pattern of renal diseases observed in native renal biopsies in adults in a single centre in Pakistan. Nephrology (Carlton) 2011;16:87-92.
26. Beisland C, Medley PC, Sander S. Nephrectomy indications complications and postoperative mortality in 646 consecutive patients. Eur Urol. 2000; 37: 58-64.
27. Tabibi A, Parvin M, Abdi H, Bashtar R, Zamani N. Correlation between size of renal cell carcinoma and its grade, stage and histological subtype. Urol J. 2008; 4: 10-13.
28. Fuhrman SA, Lasky LC, Limas C. Prognostic Significance of Morphological parameters in renal cell carcinoma. Am J Surg Path. 1982; 6: 655-63.
29. Srivastava A, Mandhani A, Kapoor R, Jain M, Dubey D, Raghavendra MA et al. Prognostic factors in patients with renal cell carcinoma: Is TNM (1997) staging relevant in Indian subpopulation. Indian J Cancer. 2004; 41:99-103
30. Jha MS, Gupta N, Agrawal S, Ansari MS, Dubey D Mandhani A et al. Single centre experience of laproscopic nephrectomy: impact of learning curve on outcome. Indian J Urol. 2007;23 (3):253-56
31. Bharti DT, Kailash S (2017) A histopathological review of Nephrectomy specimens Received in a Tertiary care hospital-A retrospective study. J Med Sci Cl Res 5(6): 23807-23810.
32. Davenport K, Temoney AG, Reeley FX: A 3 year review of British association of urological surgeons sections of endourology laproscopic nephrectomy audit. BJ U Int. 2005; 97: 333-37.
33. Ashima NA, Pushpalatha P, Krishnaraj U (2015) A Histopathological spectrum of nephrectomy specimens in a tertiary hospital in southern India. Int J Biol Med Research. 6(3): 5173-5178.
34. Beisland C, Medley PC, Sander S. Nephrectomy indications complications and postoperative mortality in 646 consecutive patients. Eur Urol. 2000; 37: 58-64.
35. Mannan R, Kaur H, Singh PA et al. A Histopathological spectrum of Renal lesions : A 3 year prospective study of a Tertiary care teaching centre. Int J Dent Med Res 2015;1(6): 11-13.
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09-09-2020
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N DK, Karamchedu S, . A. Histomorphological Spectrum of Renal diseases: A Prospective Study for A Period of Two Years. Ann of Pathol and Lab Med [Internet]. 2020 Sep. 9 [cited 2024 Nov. 19];7(8):A416-421. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/2785
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