Atypical Cervical Stromal Cells Masquerading as Malignancy
DOI:
https://doi.org/10.21276/apalm.2978Keywords:
Atypical stromal cells, Mast cells, Bizarre, Multilobed, CervixAbstract
Atypical stromal cells (ASCs) of the female genital tract are uncommon and found in various polypoid lesions of the vulva, vagina, cervix and endometrium. Although they are benign; they can be misinterpreted as a malignant. Hence it is important for a pathologist to identify the ASCs in the specimens or biopsies of lower Female genital tract and avoid over diagnosis as a malignancy. We present a case of atypical cervical stromal cells in a 45-year-old female. On microscopy, Atypical stromal cells were stellate, enlarged in size, with moderate to severely atypical hyperchromatic, multilobulated nuclei without any mitoses. Their chromatin was dense often with prominent nucleoli. This report highlights the significance of awareness about the occurrence of these cells in the female reproductive tract.
References
Monaco ML, Puzzo L, Brancato F, Torrisi A, Magro G. Endometrial atypical (bizarre) stromal cells: A potential diagnostic pitfall in biopsy. Pathol - Res Pract. 2004;200(9):625–7.
Rodrigues MI, Goez E, Larios KK, et al. Atypical stromal cells as a diagnostic pitfall in lesions of the lower female genital tract and uterus: a review and presentation of some unusual cases. Patol Rev Latinoam. 2009;47(2):103-107.
Abdul-Karim FW, Cohen RE. Atypical stromal cells of lower female genital tract. Histopathology. 1990 Sep;17(3):249–53.
Tai LH, Tavassoli FA. Endometrial Polyps With Atypical (Bizarre) Stromal Cells: Am J SurgPathol. 2002 Apr;26(4):505–9.
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Copyright (c) 2021 Shraddha Avinash Kurekar, Jayashri Popat Chaudhari, Asha Sharad Shenoy, Rachana Amit Chaturvedi
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