Glomeruli Sparing Pattern of Unclassified Renal Cell Carcinoma: A Rare Neoplasm

Authors

  • Deepa Nagarajan Pathology Department, Lilavati Hospital and Research Centre, A-791, Bandra Reclamation, Bandra west, Mumbai 400050, Maharashtra, India
  • Mrinal Mallya Histopathology Department, Saifee Hospital, 15/17, Maharshi Karve Marg, Charni Road, Mumbai 400004, Maharashtra, India
  • Mita Shah Pathology Department, Bhakti Vedanta Hospital, Srishti Complex, Bhakti Vedanta Swami Marg, Mira Road (E), Thane, Maharashtra 401107, India

DOI:

https://doi.org/10.21276/apalm.3027

Keywords:

Glomeruli sparing, Unclassified Renal cell carcinoma, Renal neoplasms

Abstract

Unclassified renal cell carcinoma (URCC), an aggressive form of renal cell carcinoma (RCC), represents 0.7– 5 .7% of renal tumours. Glomerular sparing in renal neoplasms (GS) is defined as a unique growth pattern in which tumour cells overrun intact glomeruli.

An elderly woman presented with symptoms of left flank pain for three months along with fullness in the abdomen. On clinical and radiological examination, a renal mass was revealed and operated upon. A diagnosis of URCC with a glomerular sparing pattern was made on histopathological examination. The pathological details of this rare neoplasm are presented in this article.

References

Chander B, Preet K, Bharti R, Deb P. Renal cell carcinoma, unclassified with unique features. J Cancer Res Ther. 2015;11(4):1027.

Moch H., Humphrey PA, Ulbright TM, Reuter V. WHO Classification of Tumours of the Urinary System and Male Genital Organs (4th edition). Lyon, France: International Agency for Research on Cancer; 2016.

Eble J N, Sauter G, Epstein J I, Sesterhenn I A. WHO classifications of tumor. Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs. Lyon, France: International Agency for Research on Cancer Press; 2004.

Ronny FMH, Sarungbam J, Zhong X, Yusuf Y, Yang X, Zhong M. Glomerular sparing pattern in primary kidney neoplasms: clinical, morphological and immunohistochemical study. Am J Clin Exp Urol. 2014;2(1):76–81.

Lopez-Beltran A, Kirkali Z, Montironi R, Blanca A, Algaba F, Scarpelli M, et al. Unclassified renal cell carcinoma: a report of 56 cases: UNCLASSIFIED RCC. BJU Int. 2012;110(6):786–93.

Truong LD, Shen SS. Immunohistochemical diagnosis of renal neoplasms. Arch Pathol Lab Med. 2011;135(1):92-109.

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Published

31-03-2021

How to Cite

1.
Nagarajan D, Mallya M, Shah M. Glomeruli Sparing Pattern of Unclassified Renal Cell Carcinoma: A Rare Neoplasm. Ann of Pathol and Lab Med [Internet]. 2021 Mar. 31 [cited 2024 Nov. 17];8(3):C50-53. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/3027

Issue

Vol. 8 No. 3 (2021)

Section

Case Report

License

Copyright (c) 2021 Deepa Nagarajan, Mrinal Mallya, Mita Shah

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