Pyogenic Granuloma like Kaposi Sarcoma: A Diagnosis Easily Missed
DOI:
https://doi.org/10.21276/apalm.3057Keywords:
Pyogenic granuloma, Kaposi sarcoma, HHV-8Abstract
Pyogenic granuloma-like Kaposi sarcoma (PG-like KS) is a clinicopathologic variant of Kaposi sarcoma (KS), a vascular tumor caused by human herpesvirus-8 (HHV-8). PG-like KS is a challenging entity to diagnose because its clinical and histological features encompass features of both pyogenic granuloma (PG) and KS Distinction between the two entities is clinically important as the management is different. KS patients requires evaluation of their immunodeficiency status and follow-up. Throwing a HHV-8 LNA-1 immunohistochemistry helps in clinching the diagnosis. Recognition of the precise histological features and clinical correlation can facilitate the correct diagnosis.
References
Cabibi D , Cacciatore M, Viviano E, Guarnotta C, Aragona F.J. Pyogenic granuloma –like Kaposi’s sarcoma on the hands; immunohistochemistry and huma herpes virus-8 detection. Eur Acad Dermatol Venerol.2009 May; 23 (5):587-9.
McClain CM, Haws AL, Galfione SK, Rapini RP, Hafeez Diwan A. Pyogenic granuloma like Kaposi’s sarcoma. J Cutan Pathol 2016, 43(6):549-551.
Umar A, Mohammed TT, Ahmed MS, A. Samalia MO. Pyogenic granuloma-like kaposi’s sarcoma. Ann Trop Pathol 2017; 8: 124-7.
Korekava A, Kaneko T, Nakano H, Sawamura D. Pyogenic granuloma –like Kaposi sarcoma on the first toe. JDermatol.2018; 45(7):e177-e178.
Lee MK, Ku SH, Cho EB, Park EJ, Kim KH, Kim KJ. Unusual case of pyogenic granuloma-like Kaposi's sarcoma on the sole. J Dermatol. 2015; 42 (4):425-6.
Grayson W, Pantanowitz L. Histological variants of cutaneous Kaposi sarcoma. Diagn Pathol.2008; 3:31
Urquhart JL, Uzieblo A, Kohler S. Detection of HHV-8 in pyogenic granuloma-like Kaposi sarcoma. Am J Dermatopathol.2006 Aug; 28 (4):317-21.
Scott PL, Motaparthi K, Krishnan B, Hsu S. Pyogenic granuloma-like Kaposi sarcoma: a diagnostic pitfall. Dermatol Online J. 2012; 18 (3): 4.
Strutton G and Weedon D. Acro-angiodermatitis : A simulant of Kaposi’s sarcoma. Am Journal of Dermatopathol.1987; 9(2): 85-9
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Smiley Annie George, Issam Michel Francis
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).