Pyogenic Granuloma like Kaposi Sarcoma: A Diagnosis Easily Missed

Authors

  • Smiley Annie George
  • Issam Michel Francis

DOI:

https://doi.org/10.21276/apalm.3057

Keywords:

Pyogenic granuloma, Kaposi sarcoma, HHV-8

Abstract

Pyogenic granuloma-like Kaposi sarcoma (PG-like KS) is a clinicopathologic variant of Kaposi sarcoma (KS), a vascular tumor caused by human herpesvirus-8 (HHV-8). PG-like KS is a challenging entity to diagnose because its clinical and histological features encompass features of both pyogenic granuloma (PG) and KS Distinction between the two entities is clinically important as the management is different. KS patients requires evaluation of their immunodeficiency status and follow-up. Throwing a HHV-8 LNA-1 immunohistochemistry helps in clinching the diagnosis. Recognition of the precise histological features and clinical correlation can facilitate the correct diagnosis.

Author Biographies

Smiley Annie George

Department of Histopathology, Mubarak Al Kabir Hospital, Jabriya, Kuwait. P.O.Box 43787, 32052

Issam Michel Francis

Department of Histopathology, Mubarak Al Kabir Hospital, Jabriya, Kuwait. P.O.Box 43787, 32052

References

Cabibi D , Cacciatore M, Viviano E, Guarnotta C, Aragona F.J. Pyogenic granuloma –like Kaposi’s sarcoma on the hands; immunohistochemistry and huma herpes virus-8 detection. Eur Acad Dermatol Venerol.2009 May; 23 (5):587-9.

McClain CM, Haws AL, Galfione SK, Rapini RP, Hafeez Diwan A. Pyogenic granuloma like Kaposi’s sarcoma. J Cutan Pathol 2016, 43(6):549-551.

Umar A, Mohammed TT, Ahmed MS, A. Samalia MO. Pyogenic granuloma-like kaposi’s sarcoma. Ann Trop Pathol 2017; 8: 124-7.

Korekava A, Kaneko T, Nakano H, Sawamura D. Pyogenic granuloma –like Kaposi sarcoma on the first toe. JDermatol.2018; 45(7):e177-e178.

Lee MK, Ku SH, Cho EB, Park EJ, Kim KH, Kim KJ. Unusual case of pyogenic granuloma-like Kaposi's sarcoma on the sole. J Dermatol. 2015; 42 (4):425-6.

Grayson W, Pantanowitz L. Histological variants of cutaneous Kaposi sarcoma. Diagn Pathol.2008; 3:31

Urquhart JL, Uzieblo A, Kohler S. Detection of HHV-8 in pyogenic granuloma-like Kaposi sarcoma. Am J Dermatopathol.2006 Aug; 28 (4):317-21.

Scott PL, Motaparthi K, Krishnan B, Hsu S. Pyogenic granuloma-like Kaposi sarcoma: a diagnostic pitfall. Dermatol Online J. 2012; 18 (3): 4.

Strutton G and Weedon D. Acro-angiodermatitis : A simulant of Kaposi’s sarcoma. Am Journal of Dermatopathol.1987; 9(2): 85-9

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Published

30-05-2021

How to Cite

1.
George SA, Francis IM. Pyogenic Granuloma like Kaposi Sarcoma: A Diagnosis Easily Missed. Ann of Pathol and Lab Med [Internet]. 2021 May 30 [cited 2024 Nov. 2];8(5):C82-85. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/3057

Issue

Section

Case Report