Incidence Of Hemoglobinopathies In South Indian Population – 4 Year Study

Authors

  • Kavitha - A Metropolis Healthcare limited
  • Kavita V Metropolis Healthcare limited
  • Mukilarasi . Metropolis Healthcare limited

DOI:

https://doi.org/10.21276/apalm.3236

Keywords:

Anemia, Hemoglobinopathy, South India, Thalassemia

Abstract

Background

Hemoglobinopathies are very common, but majority being asymptomatic it is under diagnosed. Hemoglobinopathies are important health care threat in tropical countries. The present study analyzed the incidence of hemoglobinpathies in south Indian population reported in regional laboratory in Chennai catering Tamil nadu and Andhra Pradesh population.

Methods

A cohort of samples which was received for abnormal hemoglobinopathy studies for evaluation of anemia and prenatal screening from Tamil nadu and Andrapradesh population for 4 years was analyzed using capillary electrophoresis method in (Sebia Minicap instrument) for incidence of hemoglobinopathies.

Result

Total number of cases studied during 4 years (2018-2022) is 17678, Of which 1194(7%) were detected with hemoglobinopathy/ abnormal hemoglobin variant.  Of which 56.28% were female and 43.72% were male. Common age group under study is 21-30(30.07%). Beta thalassemia trait was detected at the highest frequency (69.13%) followed by HbE-Beta thalaseemia(6.87%) and least being HbD homozygous.

Conclusion

Our study analyzed a cohort and reported a spectrum of hemoglobin variants and its incidence in Tamil nadu and Andhrapradesh population.

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Published

27-08-2023

How to Cite

1.
A K-, V K, . M. Incidence Of Hemoglobinopathies In South Indian Population – 4 Year Study. Ann of Pathol and Lab Med [Internet]. 2023 Aug. 27 [cited 2024 Nov. 19];10(5):A47-52. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/3236

Issue

Vol. 10 No. 5 (2023)

Section

Original Article

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Copyright (c) 2023 Kavitha - A, Kavita V, Mukilarasi .

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