Histopathological Spectrum of Ovarian Tumors at Tertiary Care Hospital – A Three Year Retrospective Study of 45 Cases

  • Ritu Radheyshyam Singh Pathology Department, GMERS Medical College and Hospital, Gotri, Vadodara, Gujarat, India
  • Aditi Dharmesh Dholakia Pathology Department, GMERS Medical College and Hospital, Gotri, Vadodara, Gujarat, India
  • Khushbu Mehulkumar Shah Pathology Department, GMERS Medical College and Hospital, Gotri, Vadodara, Gujarat, India
  • Stuti Samir Kadakia Pathology Department, GMERS Medical College and Hospital, Gotri, Vadodara, Gujarat, India
Keywords: Ovarian tumors, Surface epithelial tumors, Benign, mature cystic teratoma

Abstract

Background The ovaries are paired intra-pelvic adnexal organs of the female reproductive system involved in many important functions of the body. No organ of the body except the ovary gives rise to such a galaxy of neoplasms​​. Histopathological examination of the biopsy material is the mainstay of diagnosis, which determines the prognosis and behavior of neoplasm​​​​. Material and Methods This was a retrospective observational study. A total of 45 cases were studied. All the cases of ovarian tumors were studied with respect to age of presentation, clinical symptoms, and morphological classification. Data thus collected were analyzed and compared with other study findings. Results A total of 45 ovarian tumor cases were studied. Surface epithelial tumors were the most common ovarian tumor, constituting 53.3%, followed by germ cell tumors at 31.3%, and sex cord-stromal tumors at 15.5%. Among surface epithelial tumors, serous tumors were the most common. Abdominal pain remained the most common clinical presentation. Conclusion Ovarian tumors are the second most common neoplasm in the female genital tract following cervical cancer. Though benign tumors are more common than malignant tumors, it is important to detect the tumor at its early stage. Histopathological findings along with immunohistochemistry are helpful in early diagnosis of ovarian tumors.

References

Sharma P, Rao PS, Mogra N, Talreja K. Histopathological study of ovarian tumours in a tertiary healthcare centre of southern Rajasthan. Indian J Pathol Oncol. 2020 Nov 15;7(4):561-6.

Patel AS, Patel JM, Shah KJ. Ovarian tumors-Incidence and histopathological spectrum in tertiary care center, Valsad. IAIM. 2018 Feb 1;5(2):84-93.

Khajuria SK, Malhotra A, Verma V, Singh A, Khajuria A. Study of ovarian malignancies in a tertiary care hospital-A 3 year retrospective study. JK Sci J Med Educ Res. 2023 Jul 10;25(3):149-52.

Agrawal P, Kulkarni DG, Chakrabarti PR, Chourasia S, Dixit M, Gupta K. Clinicopathological spectrum of ovarian tumors: a 5 year experience in a tertiary health care center. J Basic Clin Reprod Sci. 2015 Jul 21;4(2):90-6.

Dutta A, Imran R, Saikia P, Borgohain M. Histopathological spectrum of ovarian neoplasms in a tertiary care hospital. Int J Contemp Med Res. 2018;8(5):1-4.

Sehgal S, Yadav R, Agarwal N, Gupta A. Histopathological spectrum of ovarian tumours: a two-year retrospective study. Int J Med Res Prof. 2020 May;6(3):50-3.

Sowmya BU, Nandish VS. Histopathological spectrum of ovarian tumors: a study of 53 cases.

Dhende PD, Patil LY, Jashnani K. Spectrum of ovarian tumors in a tertiary care hospital. Indian J Pathol Oncol. 2021;8(1):133-9.

Maru AM, Menapara CB. Histopathological study of non-neoplastic & neoplastic ovarian lesions in a tertiary care hospital in Gujarat, India. Trop J Pathol Microbiol. 2019;5(2):63-8.

Hawaldar R, Sodani S, Patidar E. Histopathological spectrum of ovarian tumours-A two year retrospective study. Indian J Pathol Oncol. 2017 Sep;4(3):450-3.

Phukan A, Borgogoi M, Ghosh S. Histopathological spectrum of ovarian tumors: an institutional perspective. Int J Res Med Sci. 2018 Aug;6:2639-43.

Sawant A, Mahajan S. Histopathological study of ovarian lesions at a tertiary health care institute. MVP J Med Sci. 2017 May 1:26-9.

Singh S, Saxena V, Khatri SL, Gupta S, Garewal J, Dubey K. Histopathological evaluation of ovarian tumors. Imp J Interdiscip Res. 2016;2(4):435-9.

Pilli GS, Suneeta KP, Dhaded AV, Yenni VV. Ovarian tumours: a study of 282 cases. J Indian Med Assoc. 2002 Jul 1;100(7):420-3.

Prakash A, Chinthakindi S, Duraiswami R, Indira V. Histopathological study of ovarian lesions in a tertiary care center in Hyderabad, India: a retrospective five-year study. Int J Adv Med. 2017 May;4(3):745.

Pandey V, Mangrulkar K, Kant Hatgyan K, Agrawal A. Histopathological spectrum of ovarian tumors in tertiary care centre of central India. MGM J Med Sci. 2023 Oct 1;10(4):621-9.

Das VS, Kathireshan C, Bhushan VP. Histopathological spectrum of ovarian neoplasms – A 3 year hospital based study. Indian J Pathol Oncol. 2023;10(4):357-61.

Published
26-05-2024
Section
Original Article