Spectrum of Patterns in Lymph Node Histopathology at A Tertiary Healthcare Centre in Hadoti Region
DOI:
https://doi.org/10.21276/apalm.3319Keywords:
Lymph node, Lymphadenopathy, Tuberculosis, Biopsy, MetastasisAbstract
Background
Lymph nodes are an integral part of immune system and, being the most widely distributed and easily accessible lymphoid tissue so they are frequently examined for diagnostic purposes. It is necessary to document the spectrum in a particular region to understand the trend and diseases occurring frequently in that region. The aim of this study is to evaluate spectrum of histopathological diagnosis among multiple etiologies of lymphadenopathy.
Methods
This is a retrospective descriptive study undertaken in the Department of Pathology, Government Medical College, Kota of all the lymph node biopsies received in our department over a period of one year from January 2023 to December 2023.
Result
A total of 102 patients were included, out of which females are 60 (59%) cases and males constituted 42 (41%) cases. Most common affected age group was 21-40 years and site was cervical with 42 (41.17%) cases. 54 cases (52.94%) showed changes of reactive lymphadenitis. Hodgkin and non-Hodgkin lymphoma ratio in male to female was 3:1, while that of tubercular lymphadenitis was 3:10. Metastatic squamous cell carcinoma and infiltrating ductal carcinoma was seen contributing to 10 (40%) cases each.
Conclusion
It is evident that most common pattern in lymph node pathology is reactive lymphadenitis, affecting age group 21-40 years, majorly affecting females. Females are mostly involved in cases of tuberculosis with ratio being 3:10. In developing country such as India, this points to frequent population exposure to infections. This could indicate a need to strengthen primary and secondary levels of preventive measures.
References
Vinay Kumar, Abul K Abbas, Jon. C. Aster. Diseases of white blood cells, lymph nodes, spleen, and thymus. In: Jerrold R. Turner. Robbins & Cotran Pathologic Basis of Disease. Tenth edition. Philadelphia: Elsevier; 2021: 588.
Pagaro PM, Banerjee B, Khandelwal A, Pandey A, Gambhir A. Spectrum of lymph nodes lesions as determined by histopathology. Med J DY Patil University 2017; 10:343-8
Shah B, Dgloorkar S, Parab S, Shah M, Vijay R. Analysis of the histopathological findings of lymph node biopsies at a tertiary care centre. Int Surg J 2023; 10:231-4
Ashwini Ashoksingh Shiledar, Amitkumar Bapuso Pandav, Santoshsing Shivramsingh Rajput, Ashish Ashoksingh Shiledar. Evaluation of Histopathological Findings in Lymph Node Lesions. Journal of Clinical and Diagnostic Research. 2022 Nov, Vol-16(11): EC37-EC41
Lali Krishnan Rajan, Priya Venugopaladas Saraswathy, Sheela Kizhuvelil Mohammed Ali, Deepthi Raj Madambithara Lekshmi. Histomorphological features of neoplastic and non- neoplastic lymph node lesions in a tertiary care hospital in South India. J Evid Based Med Healthc, Vol. 8(22), May 31,2021
Pallavi SMS, Manjunatha YA. Study of histopathological spectrum of diagnosis in lymph node biopsies in a tertiary care centre. Indian J Pathol Oncol 2019; 6(3):476-9
Khanday SA, Reshi R, Mushtaque M. Histopathology and immunohistochemistry of lymph node biopsies: A prospective study from a tertiary care hospital in Kashmir. Indian J Pathol Oncol 2019; 6(3); 400-405.
Dr. Shubhangi V Agale, Dr. Mukund B Tayade, Dr. Rachna Binayake, Dr. Charu Sethi, Dr. Grace F D’Costa, Dr. Sachin Raut. A study of evaluation of histopathological spectrum of lymph node lesions in a tertiary care centre. International journal of Medical and Health research. V0l 4(8); August 2018; 25-29.
Damle R, Suryawanshi K, Dravid NV, Newadkar DV, Prashant N. A descriptive study of histopathological patterns of lymph node biopsies in a tertiary care hospital. Deore Annals of Pathology and Laboratory Medicine. 2017; 4(2):131-136
Goyal S, Brar BK, Sehgal S. Histopathological and cytological spectrum of lymphadenopathy: a window to preliminary diagnosis. Int J Med Res Rev 2017, 5(10): 900-907.
Gupta N, Agarwal P. Spectrum of pathological lesion in superficial lymph node biopsy in a tertiary health centre of western Rajasthan. IOSR J Dent Med Sci 2016; 15(11):62-5.
Vidhyadhar R, Prakash CSR, Philip KS. Histopathological study of lymph node lesions. J Int Med Dent 2015; 3:24-33.
Roy A, Kar R, Basu D, Badhe BA. Spectrum of histopathologic diagnosis of lymph node biopsies: a descriptive study from a tertiary care centre in South India over 51/2 years. Indian J Pathol Microbiol. 2013 Apr-Jun; 56(2): 103-8.
Vachhani AB, Jasani JH, Tandon RK. Histopathological study of lymph node biopsy. Int J Biomed Adv Res 2013;4(11):790- 5.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Vandana Pathak, Bhawika Menghani, Lubhanshi Dhakar, Bhoomika Sharma
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
