Cytology of nodal Rosai-Dorfman disease: a case report
Keywords:
Emperipolesis, Rosai-Dorfman disease, Cervical lymphadenopathy, CytologyAbstract
Rosai-Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare, benign, histiocytic proliferative disorder. It can be encountered in both nodal and extra nodal locations. Fine needle aspiration technique is a simple, accurate and most economic tool, being used widely. Fourteen year old male child presented with bilateral cervical lymphadenopathy. Fine needle aspiration of cervical node revealed RDD, which was later confirmed by histopathology and immunochemistry. Owing to the rarity, cytomorphological appearance of this disease and its mimics are considered here.
References
1. Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy. Arch Pathol 1969;87: 63-70.
2. Destombes P. Adenitis with lipid excess, in children or young adults, seen in the Antilles and in Mali (4 cases). Bull SocPatholExotFiliales 1965; 58:1169-75.
3. Adrienne YS, Griffin C, Zhang PJL, Palmer JN, Gupta P. Sinus histiocytosis with massive lym-phadenopathy (Rosai-Dorfman Disease): A case report and review of 49 cases with fine needle as-piration cytology. Cyto Journal 2011; 8:3.
4. Deshpande MH, Nayak S, Munshi MM. Cy-tology of Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease) Diagnosis by fine needle aspiration. DiagnCytopathol 2000; 22: 181-5.
5. Bist SS, Bisht M, Varshnev S, Pathak VP. Rosai Dorfman syndrome with extranodal manife-station. J Assoc Physicians India. 2007; 55:445-7.
6. Humble JG, Jayne WH, Pulvertaft RJ. Biologi-cal interaction between lymphocytes and other cells. Br J Haematol. 1956;2: 283-94.
7. Middle P, Hemmerlein B, Fayyaz. Evidence for its relationship to macrophages and for a cytokine disorder. Histopathology 1999;35: 525-33.
8. Snehalatha R, Senthilnathan R, Ramani P, Herald SJ. The Rosai Dorfman Syndrome: the report of a rare case. J ClinDiagnRes. 2013;7:1519-21.
9. Vos JA, Zo SA, Barekmann CL, Jo Ann W, An-driko, Markku Miettinen, et al. Histiocytic sar-coma; a study of five cases including the histi-ocyte marker CD163. Modern pathology 2005;18:693-704.
10. Li S, Yan Z, Jhala N, Jhala D. Fine needle aspira-tion diagnosis of Rosai-Dorfman disease in an osteolytic lesion of bone. CytoJournal 2010;7:12.
11. Biswas M, Sarkar T, Das A, Naskar S. Refractory Extra nodal Rosai-Dorfman disease of cheek and upper eyelid: A rare case. Annals of Pathology and Laboratory Medicine, 2014;1:24-27
2. Destombes P. Adenitis with lipid excess, in children or young adults, seen in the Antilles and in Mali (4 cases). Bull SocPatholExotFiliales 1965; 58:1169-75.
3. Adrienne YS, Griffin C, Zhang PJL, Palmer JN, Gupta P. Sinus histiocytosis with massive lym-phadenopathy (Rosai-Dorfman Disease): A case report and review of 49 cases with fine needle as-piration cytology. Cyto Journal 2011; 8:3.
4. Deshpande MH, Nayak S, Munshi MM. Cy-tology of Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease) Diagnosis by fine needle aspiration. DiagnCytopathol 2000; 22: 181-5.
5. Bist SS, Bisht M, Varshnev S, Pathak VP. Rosai Dorfman syndrome with extranodal manife-station. J Assoc Physicians India. 2007; 55:445-7.
6. Humble JG, Jayne WH, Pulvertaft RJ. Biologi-cal interaction between lymphocytes and other cells. Br J Haematol. 1956;2: 283-94.
7. Middle P, Hemmerlein B, Fayyaz. Evidence for its relationship to macrophages and for a cytokine disorder. Histopathology 1999;35: 525-33.
8. Snehalatha R, Senthilnathan R, Ramani P, Herald SJ. The Rosai Dorfman Syndrome: the report of a rare case. J ClinDiagnRes. 2013;7:1519-21.
9. Vos JA, Zo SA, Barekmann CL, Jo Ann W, An-driko, Markku Miettinen, et al. Histiocytic sar-coma; a study of five cases including the histi-ocyte marker CD163. Modern pathology 2005;18:693-704.
10. Li S, Yan Z, Jhala N, Jhala D. Fine needle aspira-tion diagnosis of Rosai-Dorfman disease in an osteolytic lesion of bone. CytoJournal 2010;7:12.
11. Biswas M, Sarkar T, Das A, Naskar S. Refractory Extra nodal Rosai-Dorfman disease of cheek and upper eyelid: A rare case. Annals of Pathology and Laboratory Medicine, 2014;1:24-27
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Published
28-01-2014
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1.
Duraisami PR. Cytology of nodal Rosai-Dorfman disease: a case report. Ann of Pathol and Lab Med [Internet]. 2014 Jan. 28 [cited 2024 Nov. 22];2(1):C17-C20. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/78
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