Xanthogranulomatous oophoritis-masquerading as ova-rian neoplasm: report of two cases
Keywords:
Xanthogranulomatous, Oophoritis, MalignancyAbstract
Xanthogranulomatous oophritis is an unusual chronic inflammatory condition which clinically presents as a mass like lesion in the pelvic cavity. It invades the surrounding tissue and thus mimics like a tumor. Patients with xanthogranulomatous oophoritis presents with lower abdominal or suprapubic pain, fever, menorrhagia, vaginal bleeding, adnexal tenderness and rarely as a pelvic mass. Only a few cases of this entity have been reported in India.
We report two cases of xanthogranulomatous inflammation of the female genital tract presenting with unilateral ovarian masses having clinical and radiological suspicion of an ovarian tumor. Both patients underwent panhystrectomy. Gross examination revealed enlarged unilateral ovaries with multiloculated cystic cavities on cut surface. Histopathological examination revealed massive infiltration of the ovarian tissue by lipid laden histiocytes and mixed inflammatory infiltrate suggesting a diagnosis of xanthogranulomatous oophoritis. These cases mimicked as malignancy and are of interest in view of their rarity.
References
2. Kalloli M, Bafna UD, Mukherjee G, Devi UK, Gurubasavangouda, Rathod PS. A Rare Xantho-granulomatous Oophoritis Presenting as Ovarian Cancer. Online J Health Allied Scs 2012;11:11
3. Jung SE, Lee JM, Lee KY, Han KT, Hahn ST. Xanthogranulomatous oophoritis: MR imaging findings with pathological correlation.American J Roentgenol. 2002;178: 749-51.
4. Date S, Sulhyan K, Badge S, Gosavi A, Ram-teerthkar N. Xanthogranulomatous Oophoritis : Case Report. Indian Journal of Basic and Applied Medical Research 2013;7:745-9
5. Zhang XS, Dong HY, ZhangLI, Desouki MM and Zhao C; Xanthogranulomatous Inflammation of the female genital tract: Report of Three Cases. J Cancer. 2012;3:100-6.
6. Kaur S, Bodal VK, Bal MS, Bhagat R, Mohi MK. Xanthogranulomatous change-A Case Report. Research and Rewiew: J of Medical and Health Sciences 2013 ; 2: 8-9
7. Gray Y, Libbey NP. Xanthogranulomatous sal-pingitis and oophoritis: A case report and review of literatute. Arch Pathol Lab Med. 2001; 125:260-3.
8. Shukla S, Pujani M, Singh SK, Pujani M. Xan-thogranulomatous Oophritis associated with pri-mary infertility and endometriosis. Indian J Pa-thol Microbiol. 2010;53:197-8.
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