ABO blood group phenotype in and around Delhi: A study from tertiary care hospital

Authors

  • Disha Arora VMMC and Safdarjung Hospital, GGSIPU
  • Ankit Kaushik VMMC and SJH
  • D S Rawat
  • A K Mandal

Keywords:

Blood group, North India, ABO phenotype

Abstract

Background: ABO blood group shows marked geographical and racial variation. The study of regional ABO phenotype is extremely important for understanding the regional demand of rare blood groups and to tide over the massive demands in case of natural calamities or mass disaster.

Methods: A retrospective study was carried out at Department of Blood Bank and Transfusion Medicine, VMMC and Safdarjung Hospital, Delhi from January 2013 to May 2014 constituting a total of 42,456 donors including both voluntary and replacement donation. The blood group antigens were determined using electromagnetic technology and the frequency is expressed in percentage. 

Results: B phenotype is most common phenotype constituting 39.84%of total donors, followed by O phenotype with 28.56%, A with 21.24% and AB with 10.56%. A total of 91.16% donors are Rh positive, while the rest are Rh negative.

Conclusion: The ABO phenotype of Delhi and nearby regions is different from the western countries, South India and other parts of Asia. Thus this study aids in constructing a regional ABO phenotype data register for meeting regional transfusion demands.

 

References

1. Von decastella A, Sturli A. Ureber die isoag-glutinine in serumgesunder and Kranaker Men-schen. Mfiner Med WSchr. 1902;49:1090-5.
2. Schwarz HP, Dorner F. Karl landsteiner and his major contributions to haematology. British Journal of Haematology. 2003;121:556-65.
3. Enosolease EM, Bazuaye GN. Distribution of ABO and Rh-D blood groups in the Benin area of Niger-Delta: Implication for regional blood transfusion. Asian J Transfus Sci. 2008;2:3-5.
4. Hassan K, Younus M, Ikram N, Naseem L, Zaheer AH. Red cell alloimmunization in repeatedly transfused thalassemia major patients. International Journal of Pathology. 2004;2:16-9.
5. Dean L. Blood Groups and Red Cell Antigens [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2005. Chapter 2, Blood group antigens are surface markers on the red blood cell membrane. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22.
6. Castilho, Shirley L, Prearo, Verônica, Rodrigues, Kátia S, et al. Desempenho da tecnologia dos eritrócitos magnetizados (E.M.® Technology) nos testes imunoematológicos. Revista Brasileira de Hematologia e Hemoterapia. 2008; 30:374-8.
7. Nanu A, Thapliyal RM. Blood group gene fre-quency in a selected north Indian population. Indian J Med Res. 1997;106:242-6.
8. Chandra T, Gupta A. Frequency of ABO and rhesus blood groups in blood donors. Asian J Transfus Sci. 2012;6:52-3.
9. Agarwal N, Thapliyal RM, Chatterjee K. Blood group phenotype frequencies in blood donors from a tertiary care hospital in north India. Blood Res. 2013;48:51-4.
10. Sundar Periyavan, Sangeetha SK, Marimuthu P,1 Manjunath BK, Seema DK. Distribution of ABO and Rhesus-D blood groups in and around Bangalore Asian J Transfus Sci. 2010;4:41.
11. Calcutt RA, Lone MK, Ahmed S, Shah BA, Jan N. Blood groups in Kashmir valley, JK Science. 2003;5:3.
12. Alam M. ABO and Rhesus blood groups in po-tential donors at Skardu (northen areas) Pak J Pathol. 2005;16:94-7.
13. Sharma S, et al Prevalence of phenotypes and genes of ABO and Rhesus (Rh) bloodgroups in and around Amritsar district, Punjab – A four year study ( June 2007- June 2011) Abstract of 38th Annual Conference of Indian Society of Blood Transfusion and Immunohematology (ISBTI). Asian J Transfus Sci. 2012;6: 63-109.
14. Khan MS, Subhan F, Tahir F, Kazi BM, Dil AS, Sultan S, et al. Prevalence of blood groups and Rh factor in Bannu region (NWFP) Pakistan. Pakistan J Med Res. 2004;43:1.

Downloads

Published

29-01-2015

How to Cite

1.
Arora D, Kaushik A, Rawat DS, Mandal AK. ABO blood group phenotype in and around Delhi: A study from tertiary care hospital. Ann of Pathol and Lab Med [Internet]. 2015 Jan. 29 [cited 2024 Nov. 5];2(1):A26-A29. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/97

Issue

Vol. 2 No. 1 (2015)

Section

Original Article

License

Copyright (c) 2015 Disha Arora, Ankit Kaushik, D S Rawat, A K Mandal

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).