Evaluation of blood donor deferral causes: a retrospective study from South India

Authors

  • Mourouguessine Vimal Sri Manakula Vinayagar Medical College and Hospital, Puducherry - 605107
  • Srinivasan Sowmya Sri Manakula Vinayagar Medical College and Hospital
  • Anandabaskar Nishanthi Jawarhalal Institute of Postgraduate Education and Research, Puducherry
  • Gandhi Ramya Sri Manakula Vinayagar Medical College and Hospital, Puducherry

Keywords:

Blood donation, Donor deferral, Selection criteria, Prospective donors

Abstract

Background: Detailed analysis of various causes for deferral of blood donors may help medical personnel to curb the barriers that impede the blood donation. This study aims to evaluate the deferral reasons of a blood donor in our centre and to uncover the hindering factors behind the target of achieving 100% acceptance of blood donors

Methods: This is a retrospective record based study over a time period of 4 years from January 2012 to December 2015.Data were collected from the Donor deferral registry with respect to age and Gender. The causes of deferral were categorized as temporary and permanent.

Result: A total of 9557 registered donors were screened and 1421 (14.87%) were deferred. Overall, men (1258; 88.5%) were deferred more than the women (163; 11.5%). But women had higher deferral rate (163/236; 69.1%) compared to Men (1258/9321; 13.5%). Temporary deferral (78.7%) was common than the permanent deferral (21.3%). Anemia with low hemoglobin was the commonest cause of temporary deferral (31.5%) in both males and females. Hypertension was the commonest cause of permanent deferral (75.8%) constituting 16.2% of the total deferrals.

Conclusion:  Ensuring the confidentiality of history taking and examination of donors will help them to answer the questions honestly and to curb the barriers that impede the donation. Defining and educating the donor selection criteria to the community by the medical professionals and awareness and self motivation from the donors are the key factors behind achieving cent percent acceptance of blood donors.

References

1. Sareen R, Gupta GN, Dutt A, Sareen R, Gupta GN, Dutt A. Donor awareness: key to successful voluntary blood donation. F1000Research 2012. 1;29
2. Chauhan D, Desai K, Trivedi H, Agnihotri A. Evaluation of blood donor deferral causes: a tertiary-care center-based study. Int J Med Sci Public Health. 2015;1.
3. Van der Bij AK, Coutinho RA, Van der Poel CL. Surveillance of risk profiles among new and repeat blood donors with transfusion-transmissible infections from 1995 through 2003 in the Netherlands. Transfusion (Paris). 2006;46(10):1729–36.
4. Nguyen DD, Devita DA, Hirschler NV, Murphy EL. Blood donor satisfaction and intention of future donation. Transfusion (Paris). 2008 Apr;48(4):742–8.
5. Custer B, Johnson ES, Sullivan SD, Hazlet TK, Ramsey SD, Hirschler NV, et al. Quantifying losses to the donated blood supply due to donor deferral and miscollection. Transfusion (Paris). 2004 Oct;44(10):1417–26.
6. Shaz BH, James AB, Hillyer KL, Schreiber GB, Hillyer CD. Demographic variations in blood donor deferrals in a major metropolitan area. Transfusion (Paris). 2010 Apr;50(4):881–7.
7. Lawson-Ayayi S, Salmi LR. Epidemiology of blood collection in France. Eur J Epidemiol. 1999 Mar;15(3):285–92.
8. Kasraian L, Negarestani N, Kasraian L, Negarestani N. Rates and reasons for blood donor deferral, Shiraz, Iran. A retrospective study. Sao Paulo Med J. 2015 Feb;133(1):36–42.
9. Radhiga ST, Kalpana S, Selvakumar, Natarajan MV. Evaluation of Deferral Causes Among Voluntary Blood Donors in Chennai –A Retrospective Study. Int J Med Health Sci. 1357925221;2(1):42–7.
10. Arslan O. Whole blood donor deferral rate and characteristics of the Turkish population. Transfus Med Oxf Engl. 2007 Oct;17(5):379–83.
11. Newman B. Blood donor suitability and allogeneic whole blood donation. Transfus Med Rev. 2001 Jul;15(3):234–44.
12. Gajjar H, Shah FR, Shah NR, Shah CK. Whole blood donor deferral analysis at General hospital blood bank–A retrospective study. Medicine (Baltimore). 2014;235:6–13.
13. Taneja K, Bhardwaj K, Arora S, Agarwal A. Analysis of the reasons for deferral of prospective blood donors in a Tertiary Care Hospital in North India. J Appl Hematol. 2015;6(4):154.
14. Rabeya Y, Rapiaah M, Rosline H, Ahmed SA, Zaidah WA, Roshan TM. Blood pre-donation deferrals--a teaching hospital experience. Southeast Asian J Trop Med Public Health. 2008 May;39(3):571–4.
15. Charles KS, Hughes P, Gadd R, Bodkyn CJ, Rodriguez M. Evaluation of blood donor deferral causes in the Trinidad and Tobago National Blood Transfusion Service. Transfus Med. 2010 Feb 1;20(1):11–4.
16. Sundar P, Sangeetha SK, Seema DM, Marimuthu P, Shivanna N. Pre-donation deferral of blood donors in South Indian set-up: An analysis. Asian J Transfus Sci. 2010 Jul;4(2):112–5.
17. Agnihotri N. Whole blood donor deferral analysis at a center in Western India. Asian J Transfus Sci. 2010;4(2):116.
18. Mast AE. Low hemoglobin deferral in blood donors. Transfus Med Rev. 2014;28(1):18–22.
19. Radtke H, Tegtmeier J, Röcker L, Salama A, Kiesewetter H. Daily doses of 20 mg of elemental iron compensate for iron loss in regular blood donors: a randomized, double-blind, placebo-controlled study. Transfusion (Paris). 2004 Oct;44(10):1427–32.
20. Gordeuk VR, Brittenham GM, Bravo J, Hughes MA, Keating LJ. Prevention of iron deficiency with carbonyl iron in female blood donors. Transfusion (Paris). 1990 Mar 4;30(3):239–45.
21. Magnussen K, Bork N, Asmussen L. The effect of a standardized protocol for iron supplementation to blood donors low in hemoglobin concentration. Transfusion (Paris). 2008 Apr 1;48(4):749–54.
22. Gandhi MJ, Duffy K, Benike M, Jenkins S, Stubbs JR. Effect of increasing hemoglobin cutoff in male donors and increasing interdonation interval in whole blood donors at a hospital-based blood donor center. Transfusion (Paris). 2012 Sep;52(9):1880–8.
23. Mittal R, Marwaha N, Basu S, Mohan H, Ravi Kumar A. Evaluation of iron stores in blood donors by serum ferritin. Indian J Med Res. 2006 Dec;124(6):641–6.
24. Cançado RD, Chiattone CS, Alonso FF, Langhi Júnior DM, Alves R de C. Iron deficiency in blood donors. São Paulo Med J Rev Paul Med. 2001 Jul 5;119(4):132–134; discussion 131.
25. Reikvam H, Svendheim K, Røsvik AS, Hervig T, Reikvam H, Svendheim K, et al. Questionnaire-Related Deferrals in Regular Blood Donors in Norway, Questionnaire-Related Deferrals in Regular Blood Donors in Norway. J Blood Transfus J Blood Transfus. 2012 Jan 17;2012, 2012:e813231.
26. Røsvik AS, Hervig T, Wentzel-Larsen T, Ulvik RJ. Iron status in Norwegian blood donors: comparison of iron status in new blood donors registered in 1993-1997 and in 2005-2006. Vox Sang. 2009 Jan;96(1):49–55.
27. Røsvik AS, Ulvik RJ, Wentzel-Larsen T, Hervig T. The effect of blood donation frequency on iron status. Transfus Apher Sci Off J World Apher Assoc Off J Eur Soc Haemapheresis. 2009 Dec;41(3):165–9.
28. Lim JC, Tien SL, Ong YW. Main causes of pre-donation deferral of prospective blood donors in the Singapore Blood Transfusion Service. Ann Acad Med Singapore. 1993 May;22(3):326–31.
29. Maghsudlu M, Makipour M, Nasizadeh S. Evaluation of deferral causes of blood donors and relevant factors. The Scientific Journal of Iranian Blood Transfusion Organization. 2006;3(1):9-16.
30. Cheraghali A. Overview of blood transfusion system of iran: 2002-2011. Iran J Public Health. 2012;41(8):89–93.
31. Girish CJ, Chandrashekhar TN, Ramesh BK, Kantikar SM. Pre-donation deferral of whole blood donors in district transfusion centre. J Clin Diagn Res. 2012;6(1):47–50.
32. Bahadur S, Jain S, Goel RK, Pahuja S, Jain M. Analysis of blood donor deferral characteristics in Delhi, India. Southeast Asian J Trop Med Public Health. 2009 Sep;40(5):1087–91.
33. Rehman S, Arif SH, Mehdi G, Mirza S, Saeed N, et al. The Evaluation of Blood Donor Deferral Causes: A Tertiary Care Centre-based Study. J Blood Disorders Transf. 2012;3:131.
34. Bobati SS, Basavraj V, Prakash P, others. Analysis of predonation loss of blood donors due to deferrals-in a tertiary care hospital set up. Int J Health Allied Sci. 2016;5(1):15.
35. Shah SD, Shah MC, Bhatnagar NM, Gajjar MD, Soni SA, Patel TR. Analysis of blood donor deferral characteristics in a tertiary care hospital in a Blood Bank – A review. Southeast Asian J Case Rep Rev. 2013;2(5):389–95.
36. Crocco A, D’Elia D. Adverse reactions during voluntary donation of blood and/or blood components. A statistical-epidemiological study. Blood Transfus. 2007 Jul;5(3):143–52.
37. Pauwels NS, Cusack L, De Buck E, Compernolle V, Vandekerckhove P. The effect of pre-donation hypotension on whole blood donor adverse reactions: a systematic review. J Am Soc Hypertens. 2014 Jun;8(6):429–36.
38. Unnikrishnan B, Rao P, Kumar N, Ganti S, Prasad R, Amarnath A, et al. Profile of blood donors and reasons for deferral in coastal South India. Australas Med J. 2011 Jul 31;4(7):379–85.

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Published

20-12-2016

How to Cite

1.
Vimal M, Sowmya S, Nishanthi A, Ramya G. Evaluation of blood donor deferral causes: a retrospective study from South India. Ann of Pathol and Lab Med [Internet]. 2016 Dec. 20 [cited 2024 Oct. 30];3(6):A605-611. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1006

Issue

Vol. 3 No. 6 (2016): (Suppl) December

Section

Original Article

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Copyright (c) 2016 Mourouguessine Vimal, Srinivasan Sowmya, Anandabaskar Nishanthi, Gandhi Ramya

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