Histomorphological Analysis of Lesions In Nephrectomy Specimens: A 4 Years Study In A Rural Hospital In India- Our Experience.

Authors

  • Kishor H Suryawanshi ACPM MEDICAL COLLEGE DEPT OF PATHOLOGY
  • Rajshri P Damle
  • N V Dravid
  • Ashish Patil Rawandale
  • Akshay Surana

Keywords:

Chronic nonspecific pyelonephritis, end stage renal disease, nephrectomy

Abstract

Background- Kidney is involved in various pathological conditions ranging from non-neoplastic lesions to neoplastic diseases like renal cell carcinoma. Nephrectomy remains the treatment of choice for patient care in end stage renal diseases from various causes and neoplastic lesions.

Objective: To study the histomorphological spectrum and frequency of various lesions in nephrectomy specimens.

Material and methods:- A observational retrospective research study included 33 nephrectomy specimens in the department of pathology over a period of 4 years (April 2012 to April 2016).Clinical details and radiological findings were noted from records and clinico-histomorphological correlation was done.

Results: - A total of 33 nephrectomy specimens were studied. Age distribution varied from 16 to 71 years with male to female ratio of 2:1.Benign lesions comprised of maximum cases (75.76%) while malignant lesion were present in 24.24% cases. Chronic nonspecific pyelonephritis was the predominant non-neoplastic finding followed by xanthogranulomatous pyelonephritis. Renal cell carcinoma was the most common malignant lesion in this study.

Conclusion: Chronic nonspecific pyelonephritis leading to end stage renal disease is the commonest causative factor in our region ; may be due to consumption of hard water in rural areas.


DOI: 10.21276/APALM.1111

Author Biography

Kishor H Suryawanshi, ACPM MEDICAL COLLEGE DEPT OF PATHOLOGY

Department Of Pathology

Associate Professor

References

1. Mahesh KU, Yelikar BR,Patil G, Karigoudar MH, Pande P,Patil SB. Spectrum of Histopathological lesions in Nephrectomy specimens – A two year study in a tertiary care hospital. Int J of Research in Pharmaceutical and Biomedical Sciences 2012;3(4):1787-90.
2. Divyashree BN, Venkatesh K, Madhusudhan HR, Hanumantha Raju BK. “Pathological Spectrum of Non-Neoplastic Diseases in the Nephrectomy Specimens”. Journal of Evidence based Medicine and Healthcare 2014; 1(15): 1909-1920.
3. Algaba F, Trias I, Scarpelli M, Boccon-Gibod L, Kirkali Z, Poppel HV. Handling and pathology reporting of renal tumor specimens. Eur Urol 2004;45: 437-43
4. Harry W. Herr. A history of partial nephrectomy for renal tumours. J Urol. 2005; 173(3): 705-708.
5. Rafique M. Nephrectomy: Indications, complications and mortality in 154 consecutive patients. J Pak Med Assoc 2007;57:308-11.
6. El Malik EM, Memon SR, Ibrahim AL, Al Gizawi A, Ghali AM. Nephrectomy in Adults: Asir Hospital Experience. Saudi J Kidney Dis Transpl 1997;8:423-7.
7. Aiman A, Singh K, Yasir M. Histopathological spectrum of lesions in nephrectomy specimens: A five-year experience in a tertiary care hospital. J Sci Soc 2013;40:148-54.
8.Huland H, Busch R. Chronic pyelonephritis as a cause of end stage renal disease. J Urol 1982;127:642-3.
9. Popat VC, Kumar MP, Udani D, Mundra MP, Vora DN, Porecha MM. A study on culprit factors ultimately demanding nephrectomy. Internet J Urol 2010;7.
10.Beisland C, Medby PC, Sander S, Beisland HO. Nephrectomy indications, complications and post-operative mortality in 646 consecutives patients. Eur Urol 2000;37:58-64.
11.Eke N, Echem RC. Nephrectomy at the University of Port Harcourt Teaching Hospital: a ten year experience. Afr J Med Sci 2003;32:173-77.
12. Ghalayini IF. Pathological spectrum of nephrectomies in a general hospital. Asian J Surg 2002;25:163-9.

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Published

04-06-2017

How to Cite

1.
Suryawanshi KH, Damle RP, Dravid NV, Rawandale AP, Surana A. Histomorphological Analysis of Lesions In Nephrectomy Specimens: A 4 Years Study In A Rural Hospital In India- Our Experience. Ann of Pathol and Lab Med [Internet]. 2017 Jun. 4 [cited 2024 Dec. 26];4(3):A230-235. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1111

Issue

Vol. 4 No. 3 (2017)

Section

Original Article

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Copyright (c) 2017 Kishor H Suryawanshi, Rajshri P Damle, N V Dravid, Ashish Patil Rawandale, Akshay Surana

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