Comparison Of Diagnostic Accuracy Of BIRADS Score With Pathologic Findings In Breast Lumps

Authors

  • Navya BN KVG MEDICAL COLLEGE AND HOSPITAL
  • Shalu Thomas
  • Rudresh Hiremath
  • Sathyavathi R Alva

Keywords:

BIRADS, Fine-needle aspiration cytology, Histopathology, Breast Lump.

Abstract

Background: Breast lump is one of the commonest complaints with which patients present in breast clinics. As approximately 10% of breast masses ultimately lead to a diagnosis of breast cancer, it is important for women with a breast lump to receive appropriate evaluation. A confident diagnosis can be made in 95% of the cases through a combination of clinical examination, imaging and fine needle aspiration cytology. Histopathology is the gold standard for diagnosis.

Methods: This is a prospective study conducted in the Department of Pathology, K.V.G Medical College, Sullia on 50 patients who presented with clinically palpable breast lump. Patients were subjected to sonomammography and Breast  Imaging Reporting and Data System (BIRADS) scoring followed by FNAC and histopathological examination. Sensitivity, specificity, accuracy, positive and negative predictive values of sonomammogram in relation to the BIRADS score and FNAC taking histopathology as the gold standard was calculated.

Result: FNAC had significantly higher sensitivity, specificity ,positive and negative predictive values and accuracy compared to sonographical diagnosis using BIRADS Score.   

Conclusion: FNAC could be considered as the first method to evaluate breast lesions, recognized by means of imaging techniques.


DOI: 10.21276/APALM.1124

References

1. Shrestha MK, Ghartimagar D, Ghosh A, Shrestha E, Bolar P. Significance of quadruple assessment of breast lump – A Hospital based study. Journal of Pathology of Nepal. 2014;4:630-4.
2. Lalchan S, Thapa M, Sharma P, Shrestha S, Subash K, Pathak M et al.
Role of Mammography Combined with Ultrasonography in Evaluation of Breast Lump. American Journal of Public Health Research. 2015;3(5A):95-8.
3. Chairat R, Puttisri A, Pamarapa A, Samintharapanya S, Tawichasri C, Patumanod J. Are Both Ultrasonography and Mammography Necessary for Cancer Investigation of Breast Lumps in Resource-Limited Countries? ISRN Oncology. 2013;Article ID 257942, doi:10.1155/2013/257942.
4. Arsalan F, Subhan A, Rasul S, Jalali U, Yousuf M, Mehmood Z et al. Sensitivity and specificity of BI-RADS scoring system in carcinoma of breast. Journal of Surgery Pakistan. 2010;15(1):38-43.
5. Phurailatpam J, Sakalecha A, Prasad CS, Kumar BN, Hegde P. Evaluation Of
Mammography, Sonomammography In Correlation With Fine Needle
Aspiration Of Breast Lumps. Int J Biol Med Res. 2014;5(3):4370-6.
6. Quershi S A, Rehman K, Muhammad D, Khan M I, Jaffra H. Validity of Mammogram according to Bi-RADS Scoring In Relation with Histopathology among Females Presenting with Clinically Palpable Breast lump or Nipple discharge. Ann Pak Inst Med Sci. 2014;10(3):150-4.
7. Daramola AO, Odubanjo MO, Obiajulu FJ, Ikeri NZ. Correlation between Fine needle aspiration cytology and histology for palpable breast masses in a Nigerian tertiary health institution. International Journal of breast Cancer. 2015;Article ID 742573, doi:10.1155/2015/742573.
8. Yalavarthi S, Tanikella R, Prabhala S, Tallam US. Histopathological and cytological correlation of tumors of breast. Medical Journal of Dr. D.Y. Patil University. 2014;7 (3):326-31.
9. Taori K, Dhakate S, Rathod J, Hatgaonkar A, Disawal A, Wavare P et al. Evaluation of Breast Masses Using Mammography and Sonography as First Line Investigations. Open Journal of Medical Imaging. 2013;3:40-49.doi.org/10.4236/ojmi.2013.31006.
10. Heinig J, Witteler R, Schmitz R, Kiesel L, Steinhard J. Accuracy of classification of breast ultrasound findings based on criteria used for BI-RADS. Ultrasound Obstet Gynecol. 2008;32:573–78.
11. TakhellambamYS, Lourembam SS, Sapam OS, Kshetrimayum RS, Thoujam BS, Khan T. Comparison of Ultrasonography and Fine Needle Aspiration Cytology in the Diagnosis of Malignant Breast Lesions. Journal of Clinical and Diagnostic Research. 2013;7(12):2847-50.
12. Shumaila SM, Tayyiba A, Safdar AM. Mammographic – Sonographic co-relation in the diagnosis of breast lump. Biomedica. 2008;24:147-51.
13. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid Breast Nodules: Use of Ultrasonography to Distinguish between Benign and Malignant Lesions. Radiology. 1995;196(1):123-34.
14. Emine D, Suzana M, Halit Y, Arben K. Comparative accuracy of mammography and ultrasound in women with breast symptoms according to age and breast density. Bosn J Basic Med Sci. 2009;9:131-6.
15. Vala MT, Goswami A, Suri SK. Comparative study of cytological and histopathological finding in breast lesion. IOSR Journal of Dental and Medical Sciences. 2014;13(7):05-07.
16. Qin Z, NieShigui, Yuhua C, Limei Z. Fine Needle Aspiration Cytology of Breast Lesions: Analysis of 323 Cases. The Chinese-German Journal of Clinical Oncology. 2004;3(3):172-4.
17. Tiwari M. Role of FNAC in diagnosis of breast lumps. Kathmandu University Medical Journal. 2007;5:215-17.
18. Bukhari MH, Arshad M, Jamal S, Niazi S, Bashir S, Bakhshi IM. Use of fine-needle aspiration in the evaluation of breast lumps. Patholog Res Int. 2011;doi:10.4061/2011/689521
19. Velu ARK, Srinivasamurthy BC, Rani J. Cytological evaluation of benign breast lesions with histopathological correlation. Indian Journal of Pathology and Oncology. 2016;3(1):7-10.
20. Moschetta M, Telegrafo M, Carluccio DA, Jablonska JP, Rella L, Serio G et al. Comparison between fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in the diagnosis of breast lesions. G Chir. 2014;35(7/8):171-6.

Downloads

Published

04-06-2017

How to Cite

1.
BN N, Thomas S, Hiremath R, Alva SR. Comparison Of Diagnostic Accuracy Of BIRADS Score With Pathologic Findings In Breast Lumps. Ann of Pathol and Lab Med [Internet]. 2017 Jun. 4 [cited 2024 Dec. 21];4(3):A236-242. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1124

Issue

Vol. 4 No. 3 (2017)

Section

Original Article

License

Copyright (c) 2017 Navya BN, Shalu Thomas, Rudresh Hiremath, Sathyavathi R Alva

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).