Impact of histopathological examination of appendix in context to clinical management of patients
Keywords:
appendicitis, unusual findings, valueAbstract
Background: Acute appendicitis is one of the common conditions requiring emergency surgery. In routine practice , appendix is sent for histolopathological examination only when the operative findings are inconclusive. In view of this trend in clinical practice this study was carried out to assess the value of routine histopathological examination of surgically resected appendices, to review spectrum of histopathological diagnosis of appendectomy done at our institute over a 22 months period, some of which would further have effect on patient management and prognosis.
Methods: A retrospective study was done including  appendicectomy specimens received at histopathology section of Department of Pathology at Tertiary care centre in South Gujarat during January 2015 till October 2016 .
Result: Total 400 cases were reviewed . Out of these, clinically suspected appendicitis was found in 365 (91.3 %) cases including spectrum of appendicitis (acute, subacute, chronic, ulcerative, suppurative, necrotizing, gangrenous, acute with periappendicits,acute on chronic) . Unusual unexpected findings were found in 20 (5 %) cases[tuberculosis, amoebiasis, faecolith, congestion with sickle RBCs, mucocele and neoplastic lesions  including carcinoid, adenocarcinoma, mucinous cystadenoma(low grade appendiceal mucinous neoplasm)].
Conclusion:Â Though majority of cases had the usual features, 20 of these 400 specimen (5 %) had an impact on patient management or outcome. They were not suspected on macroscopic examination at the time of surgery and would have been missed had the specimens not been examined microscopically. Intraoperative diagnosis of surgeon is therefore unreliable in detecting abnormalities of appendix. This study supports the sending of all appendicectomy specimens for routine histopathological examination.
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