Castleman Disease- An Uncommon And Intriguing Condition Revisited: A Report Of Two Cases

Authors

  • Shubhangi Vinayak Agale Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)
  • Sushama N. Ramraje Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)
  • Sameer Ansari Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)
  • Pinkesh Gugaliya Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)
  • Banasri Devi Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)
  • Grace F. D’Costa Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)

Keywords:

Lymph node, Castleman disease, Hyaline vascular, Mixed variant

Abstract

Castleman disease (CD) also called as angiofollicular hyperplasia or giant lymph node hyperplasia of unknown cause is a benign lymphoproliferative disorder. It is a localised (unicentric) or disseminated (multicentric) disease. This disease is uncommon with an incidence of 25 cases per million person per year. Castleman disease is a heterogeneous group of disorders with four characteristic histological variants. The etiology of this disease is poorly understood.
We report two cases of CD, one presenting with a neck mass and the other presenting with para-aortic and mesenteric lymphadenopathy which were classified as hyaline vascular type and mixed type of CD respectively.

DOI: 10.21276/APALM.1559

Author Biographies

Shubhangi Vinayak Agale, Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)

Associate Professor

Dept of Pathology

Grant Govt Medical College, Mumbai.

Sushama N. Ramraje, Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)

Department of Pathology, Grant Government Medical College, Mumbai Maharashtra 400008

Sameer Ansari, Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)


Department of Pathology, Grant Government Medical College, Mumbai Maharashtra 400008

Pinkesh Gugaliya, Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)

Department of Pathology, Grant Government Medical College, Mumbai Maharashtra 400008

Banasri Devi, Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)


Department of Pathology, Grant Government Medical College, Mumbai Maharashtra 400008

Grace F. D’Costa, Pathology, Grant Government Medical College And Sir JJ Group Of Hospitals(India)

Department of Pathology, Grant Government Medical College, Mumbai Maharashtra 400008

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Published

12-01-2018

How to Cite

1.
Agale SV, Ramraje SN, Ansari S, Gugaliya P, Devi B, D’Costa GF. Castleman Disease- An Uncommon And Intriguing Condition Revisited: A Report Of Two Cases. Ann of Pathol and Lab Med [Internet]. 2018 Jan. 12 [cited 2024 Oct. 30];5(1):C1-5. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1559

Issue

Vol. 5 No. 1 (2018)

Section

Case Report

License

Copyright (c) 2018 Shubhangi Vinayak Agale, Sushama N. Ramraje, Sameer Ansari, Pinkesh Gugaliya, Banasri Devi, Grace F. D’Costa

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