Spectrum of Malignant Lymphoma in a Tertiary Care Hospital of North Eastern India

Authors

  • Mondita Borgohain Department of Pathology, Assam Medical College & Hospital, Dibrugarh(India)
  • Gayatri Gogoi Department of Pathology, Assam Medical College & Hospital, Dibrugarh(India)
  • Niva Sharma Department of Pathology, Assam Medical College & Hospital, Dibrugarh(India)
  • Upam Sharma Department of Pathology, Assam Medical College & Hospital, Dibrugarh(India)
  • Kamal Kishore Chelleng Department of Pathology, Assam Medical College & Hospital, Dibrugarh(India)
  • Jyoti Bikash Saikia Department of Pathology, Assam Medical College & Hospital, Dibrugarh(India)

Keywords:

Malignant Lymphoma, Non Hodgkins Lymphoma, Hodgkins Lymphomas, Diffuse large B cellLymphoma, Histopathology, Immunohistochemistry.

Abstract

Background: The term malignant Lymphomas embrace a variable group of Proliferative diseases that originate in the Lymph node or extra nodal Lymphatic Tissue. It constitutes 3.69% of all Malignancies World Wide. The incidence of Lymphoma exhibits a marked Geographic variation in the World.

Methods: The study included58 patients who were histologically diagnosed  as Malignant lymphomas in our hospital, the paraffin embedded blocks of these cases were evaluated by   a panel of immunohistochemistry markers by taking proper controls and using the standard protocol. Statistical analysis were performed by SPSS software.

Results: Out of the 58 cases of Malignant Lymphoma 47 were diagnosed as Non Hodgkins Lymphoma and 11 cases (19%) as Hodgkins Lymphoma. Of these 58 cases of Malignant Lymphoma, adults were 51 and paediatric cases were 7, male female ratio was 2.6:1 and Non Hodgkins Lymphoma was Commoner. B cell Lymphomas were the predominant type accounts for 74.5% of all Non Hodgkins Lymphoma cases of these B cell Lymphomas Diffuse large B cell Lymphoma was the Predominant type.

Among the T cell Lymphomas Anaplastic large cell Lymphoma was the commonest subtype. Nodular Sclerosis Cases were seen most commonly in the Hodgkins Category. Extra nodal Lymphomas were also seen in 35.6% cases with Tonsil being the commonest site.

Conclusion: Non Hodgkins Lymphoma was significantly more common in this region and diffuse large B cell Lymphoma was the predominant type. A combination of Histopathology and a Meticulous Immunohistochemistry helps in properly solving the diagnostic challenges.


DOI:10.21276/APALM.1631

Author Biography

Mondita Borgohain, Department of Pathology, Assam Medical College & Hospital, Dibrugarh(India)

Department of Pathology and Professor

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Published

22-03-2018

How to Cite

1.
Borgohain M, Gogoi G, Sharma N, Sharma U, Chelleng KK, Saikia JB. Spectrum of Malignant Lymphoma in a Tertiary Care Hospital of North Eastern India. Ann of Pathol and Lab Med [Internet]. 2018 Mar. 22 [cited 2025 May 9];5(3):A188-193. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1631

Issue

Vol. 5 No. 3 (2018)

Section

Original Article

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Copyright (c) 2018 Mondita Borgohain, Gayatri Gogoi, Niva Sharma, Upam Sharma, Kamal Kishore Chelleng, Jyoti Bikash Saikia

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