Skin Adnexal Tumors: A histopathological study of 60 cases at a tertiary care centre.
Keywords:
Adnexal, Differentiation, Histopathology, Skin.Abstract
Background: Skin adnexal tumors (SATs) are one of the most challenging areas of dermatopathology. SAT encompasses a large and a diverse group of benign and malignant neoplasms which exhibit morphological differentiation towards one of the different types of adnexal epithelium present in normal skin. The aim of this study is to study the spectrum and microscopic features of skin adnexal tumors.
Methods: A cross-sectional, descriptive study was conducted over a period of 5 years in the Department of Pathology, VIMSAR, Burla. Formalin fixed, paraffin embedded tissue sections were stained with hematoxylin and eosin stain for histopathological analysis.
Result: Out of total 60 cases diagnosed as adnexal neoplasm 27(45%) tumors were with sweat gland differentiation followed by tumors with sebaceous differentiation 19(31.66%) and follicular differentiation 14(23.33%). The age ranged from 11 years to 75 years and male to female ratio was 1.7:1. Most of the tumors (78.33%) were benign while only 21.66% were malignant. Eccrine poroma was the most common benign tumor while sebaceous carcinoma was the most common malignant tumor.
Conclusion: Architectural features are of great importance in differentiating benign tumors from malignant tumors in histopathology.
DOI:10.21276/APALM.1787
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