Cellular Angiofibroma: a rare vulvar neoplasm distinct from Aggressive Angiomyxoma

Authors

  • Jasvinder Kaur Bhatia Armed Forces medical college Pune
  • R Nangia

Keywords:

Cellular Angiofibroma, Vulva, Immunohistochemistry, Aggressive angiomyxoma.

Abstract

Cellular angiofibroma (CA) is a rare benign mesenchymal neoplasm of the genital region of both the genders. In women, it arises in late reproductive age and can be cured by complete local excision. It is characterized by a bland spindle cell population and numerous small- to medium-sized vessels with hyalinization.  We report a rare case in a postmenopausal woman with a view to highlight the importance of differentiating it from similar more aggressive tumours like aggressive angiomyxoma.  A 56 year old woman presented with superficial painless swelling of the vulva and the  mass was surgically excised. Histological examination revealed spindle cell proliferation and hyalinised blood vessels in a loosely cellular stroma.  Immunohistochemistry revealed  positivity for vimentin  and CD34 and positivity for ER & PR. 

 

 

Cellular angiofibroma (CA) is a rare benign mesenchymal neoplasm of the genital region of both the genders. In women, it arises in late reproductive age and can be cured by complete local excision. It is characterized by a bland spindle cell population and numerous small- to medium-sized vessels with hyalinization.  We report a rare case in a postmenopausal woman with a view to highlight the importance of differentiating it from similar more aggressive tumours like aggressive angiomyxoma.  A 56 year old woman presented with superficial painless swelling of the vulva and the  mass was surgically excised. Histological examination revealed spindle cell proliferation and hyalinised blood vessels in a loosely cellular stroma.  Immunohistochemistry revealed  positivity for vimentin  and CD34 and positivity for ER & PR. 

Author Biography

Jasvinder Kaur Bhatia, Armed Forces medical college Pune

Reader

Department of Pathology

References

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Published

01-11-2015

How to Cite

1.
Bhatia JK, Nangia R. Cellular Angiofibroma: a rare vulvar neoplasm distinct from Aggressive Angiomyxoma. Ann of Pathol and Lab Med [Internet]. 2015 Nov. 1 [cited 2024 Dec. 21];2(4):C213-217. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm403

Issue

Vol. 2 No. 4 (2015)

Section

Case Report

License

Copyright (c) 2015 Jasvinder Kaur Bhatia, R Nangia

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