Spectrum of fibro osseous lesions: a retrospective study
Keywords:
Fibro-osseous, Fibrous Dysplasia, Cemento-ossifying FibromaAbstract
Background: Fibroosseous lesions (FOL) are a group of lesions which affect the jaw and the craniofacial bones and are a challenge to pathologists and clinicians in their diagnosis and treatment. It includes developmental lesions, reactive lesions and neoplasms. Many other lesions share the clinical, radiological and histopathological features of FOL. The identification of benign FOL and their sub classification is important because the therapeutic management varies depending on the actual disease process. The aim of this study was to analyse the spectrum of FOL and its mimickers that presented in our hospital and to study its clinicopathological aspects.
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Methods: A retrospective analysis of 31 cases of benign FOL and its mimickers which presented between 2007 & 2013 was done in the Dept of pathology. Clinical data and X-ray findings were obtained from the medical records department. Â
Result: Among 31 cases studied, 15 cases were diagnosed as FOLs and 16 as fibro-osseous like lesions. FOLs were most commonly seen in females in 1st to 3rd decade with a predilection for facial bones. Commonest lesion was fibrous dysplasia - 11 cases (73.3%), followed by 2 cases each of cemento ossifying fibroma and osteofibrous dysplasia (13.3%).The commonest diseases among the mimickers included Aneurysmal Bone Cyst- 6 cases (37.5%), followed by osteoid osteoma - 4 cases (25%), 2 cases (12.5%) each of pagets disease of bone & osteoblastoma and 1 case (6.3%) each of brown tumour of hyperparathyroidism and cementoblastoma and these were most commonly seen in long bones. In histopathology, FOLs show densely collagenous fibroblastic tissue containing metaplastic bone where as fibro osseous like lesions exhibit less fibrous tissue in the stroma.
Conclusion: A definitive diagnosis of a FOLs and its differentiation from its mimickers requires correlation of histological features with the clinical, radiographic and intraoperative findings. Â
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