Primary Intracerebral Myxopapillary Ependymoma : A Rare Case Report
Keywords:
Myxopapillary ependymoma, Cerebral hemisphere, Frontal lobeAbstract
Myxopapillary ependymoma (MPE) is a variant of ependymoma occurring almost exclusively in the conus medullaris or filum terminale. Myxopapillary ependymoma primarily in the brain is extremely rare. Here we report the case of a 21 year female with a right frontal myxopapillary ependymoma which did not demonstrate any connection to the lateral ventricles. Patient is presented with complaint of headache and vomiting with no history of convulsion, loss of consciousness. On radiological examination, MRI of brain revealed an ill-defined, cystic mass lesion in frontal lobe. On histopathological examination it was reported as myxopapillary ependymoma. This is the sixteenth reported case of histologically proven primary myxopapillary intracranial ependymoma and fourth cases of supratentorial intaparenchymal lesion.Â
References
1. Kernohan JW. Primary tumors of the spinal cord and intradural ï¬lum terminale.In:Penï¬eldW,editor.Cytology and cellular pathology of the nervous system, vol.3. New York: Paul B. Hoeber; 1932. p.993–1025.
2. Sonneland PR, Scheithauer BW, Onofrio BM. Myxopapillary ependymoma. A clinicopathologic and immunocytochemical study of 77 cases. Cancer 1985; 56:883–93.
3. Sato H, Ohmura K, Mizushima M, et al. Myxopapillary ependymoma of the lateral ventricle. A study on the mechanism of its stromal myxoid change. Acta Pathol Jpn 1983;33:1017–25.
4. Maruyama R, Koga K, Nakahara T, et al. Cerebral myxopapillary ependymoma. Hum Pathol 1992;23: 960–2.
5. Warnick RE, Raisanen J, Adornato BT, et al. Intracranial myxopapillary ependymoma: case report. J Neurooncol 1993;15:251–6.
6. Matyja E, Naganska E, Zabek M, et al. Myxopapillary ependymoma of the lateral ventricle with local recurrences: histopathological and ultrastructural analysis of a case. Folia Neuropathol 2003;41:51–7.
7. Ralte AM, Rao S, Sharma MC, Suri A, Gaikwad S, Sarkar C. Myxopapillary ependymoma of the temporal lobe--report of a rare case of temporal lobe epilepsy. Clin Neuropathol. 2004 Mar-Apr;23(2):53-8.
8.Tseng YC, Hsu H-L, Jung SM, Chen CJ. Primary intracranial myxopapillary ependymomas: report of two cases and review of the literature. Acta Radiol 2004;45: 344–347.
9. Tzerakis N, Georgakoulias N, Kontogeorgos G, Mitsos A, Jenkins A, Orphanidis G. Intraparenchymal myxopapillary ependymoma: case report. Neurosurgery. 2004 Oct;55(4):981.
10. Lim SC, Jang SJ. Myxopapillary ependymoma of the fourth ventricle. Clin Neurol Neurosurg. 2006 Feb;108(2):211-4.
11. Sparaco M, Morelli L, Piscioli I, et al: Primary myxopapillary ependymoma of the cerebellopontine angle: Report of a case. Neurosurg Rev 32:241-244; discussion 244, 2009
12. DiLuna ML, Levy GH, Sood S, Duncan CC. Primary myxopapillary ependymoma of the medulla: case report. Neurosurgery 2010;66(6):E1208–E1209
13. Shapey J, Barazi S, Bodi I, Thomas N. Myxopapillary ependymoma of the cerebellopontine angle: Retrograde metastasis or primary tumour? Br J Neurosurg 2011;25:122-3.
14. Margetis K, Koutsarnakis C, Stranjalis G: Primary cerebellar myxopapillary ependymoma. J Neurooncol 104:839-840, 2011
15. Chakraborti S, Govindan A, Alapatt JP, Radhakrishnan M, Santosh V. Primary myxopapillary ependymoma of the fourth ventricle with cartilaginous metaplasia: a case report and review of the literature. Brain Tumor Pathol. 2012 Jan;29(1):25-30.
16. Wang M, Wang H, Zhou Y, Zhan R, Wan S. Myxopapillary ependymoma in the third ventricle area and sacral canal: dropped or retrograde metastasis? Neurol Med Chir (Tokyo). 2013;53(4):237-41.
17. Chamberlain MC. Ependymomas. Curr Neurol Neurosci Rep 2003;3:193–9.
18. Mork SJ, Loken AC. Ependymoma: a follow-up study of 101 cases. Cancer 1977;40:907–15.
19. Helwig EB, Stern JB. Subcutaneous sacrococcygeal myxopapillary ependymoma. A clinicopathologic study of cases 30 cases. Am J Clin Patholsemi 1984;81:156–61.
20. Hanchey RE, Stears JC, Lehman RA, et al. Interhemispheric ependymoma mimicking falx meningioma. Case report. J Neurosurg 1976;45:108–12.
21. Marks JE, Adler SJ. A comparative study of ependymomas by site of origin. Int J Radiat Oncol Biol Phys 1982;8:37–43.
22.. Moutaery K, Aabed MY, Ojeda VJ. Cerebral and spinal cord myxopapillary ependymomas: a case report. Pathology 1996;28:373–6.
23.. Kittel K, Gjuric M, Niedobitek G. Metastasis of a spinal myxopapillary ependymoma to the inner auditory canal. HNO 2001;49:298–302.
24. Liborio R, Pais RF, Soares GB, et al. Medullary and intracranial metastases of myxopapillary ependymoma. Acta Med Port 2001;14:133–8.
2. Sonneland PR, Scheithauer BW, Onofrio BM. Myxopapillary ependymoma. A clinicopathologic and immunocytochemical study of 77 cases. Cancer 1985; 56:883–93.
3. Sato H, Ohmura K, Mizushima M, et al. Myxopapillary ependymoma of the lateral ventricle. A study on the mechanism of its stromal myxoid change. Acta Pathol Jpn 1983;33:1017–25.
4. Maruyama R, Koga K, Nakahara T, et al. Cerebral myxopapillary ependymoma. Hum Pathol 1992;23: 960–2.
5. Warnick RE, Raisanen J, Adornato BT, et al. Intracranial myxopapillary ependymoma: case report. J Neurooncol 1993;15:251–6.
6. Matyja E, Naganska E, Zabek M, et al. Myxopapillary ependymoma of the lateral ventricle with local recurrences: histopathological and ultrastructural analysis of a case. Folia Neuropathol 2003;41:51–7.
7. Ralte AM, Rao S, Sharma MC, Suri A, Gaikwad S, Sarkar C. Myxopapillary ependymoma of the temporal lobe--report of a rare case of temporal lobe epilepsy. Clin Neuropathol. 2004 Mar-Apr;23(2):53-8.
8.Tseng YC, Hsu H-L, Jung SM, Chen CJ. Primary intracranial myxopapillary ependymomas: report of two cases and review of the literature. Acta Radiol 2004;45: 344–347.
9. Tzerakis N, Georgakoulias N, Kontogeorgos G, Mitsos A, Jenkins A, Orphanidis G. Intraparenchymal myxopapillary ependymoma: case report. Neurosurgery. 2004 Oct;55(4):981.
10. Lim SC, Jang SJ. Myxopapillary ependymoma of the fourth ventricle. Clin Neurol Neurosurg. 2006 Feb;108(2):211-4.
11. Sparaco M, Morelli L, Piscioli I, et al: Primary myxopapillary ependymoma of the cerebellopontine angle: Report of a case. Neurosurg Rev 32:241-244; discussion 244, 2009
12. DiLuna ML, Levy GH, Sood S, Duncan CC. Primary myxopapillary ependymoma of the medulla: case report. Neurosurgery 2010;66(6):E1208–E1209
13. Shapey J, Barazi S, Bodi I, Thomas N. Myxopapillary ependymoma of the cerebellopontine angle: Retrograde metastasis or primary tumour? Br J Neurosurg 2011;25:122-3.
14. Margetis K, Koutsarnakis C, Stranjalis G: Primary cerebellar myxopapillary ependymoma. J Neurooncol 104:839-840, 2011
15. Chakraborti S, Govindan A, Alapatt JP, Radhakrishnan M, Santosh V. Primary myxopapillary ependymoma of the fourth ventricle with cartilaginous metaplasia: a case report and review of the literature. Brain Tumor Pathol. 2012 Jan;29(1):25-30.
16. Wang M, Wang H, Zhou Y, Zhan R, Wan S. Myxopapillary ependymoma in the third ventricle area and sacral canal: dropped or retrograde metastasis? Neurol Med Chir (Tokyo). 2013;53(4):237-41.
17. Chamberlain MC. Ependymomas. Curr Neurol Neurosci Rep 2003;3:193–9.
18. Mork SJ, Loken AC. Ependymoma: a follow-up study of 101 cases. Cancer 1977;40:907–15.
19. Helwig EB, Stern JB. Subcutaneous sacrococcygeal myxopapillary ependymoma. A clinicopathologic study of cases 30 cases. Am J Clin Patholsemi 1984;81:156–61.
20. Hanchey RE, Stears JC, Lehman RA, et al. Interhemispheric ependymoma mimicking falx meningioma. Case report. J Neurosurg 1976;45:108–12.
21. Marks JE, Adler SJ. A comparative study of ependymomas by site of origin. Int J Radiat Oncol Biol Phys 1982;8:37–43.
22.. Moutaery K, Aabed MY, Ojeda VJ. Cerebral and spinal cord myxopapillary ependymomas: a case report. Pathology 1996;28:373–6.
23.. Kittel K, Gjuric M, Niedobitek G. Metastasis of a spinal myxopapillary ependymoma to the inner auditory canal. HNO 2001;49:298–302.
24. Liborio R, Pais RF, Soares GB, et al. Medullary and intracranial metastases of myxopapillary ependymoma. Acta Med Port 2001;14:133–8.
Downloads
Published
05-11-2016
How to Cite
1.
Patangia P, Rai NN, Saxena R, Mandawat PS. Primary Intracerebral Myxopapillary Ependymoma : A Rare Case Report. Ann of Pathol and Lab Med [Internet]. 2016 Nov. 5 [cited 2024 Nov. 19];3(5):C236-240. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm619
Issue
Section
Case Report
License
Copyright (c) 2016 Priyanka Patangia, Naresh N. Rai, Rajeev Saxena, Preetam Singh Mandawat
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).