Warthin like variant of Papillary carcinoma thyroid against the background of Hashimotos thyroiditis : a case report

Authors

  • Swati Patki LTMMC &LTMGH ,SION ,MUMBAI
  • Ganesh R Kshirsagar
  • Sheetal Yadav
  • Nitin Gadgil

Keywords:

Papillary thyroid carcinoma, Warthin-like variant of PTC.

Abstract

Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of the thyroid gland with many variants . The Warthin-like variant of PTC (WLPTC) is a rare accounting for 1-2% of  PTC that is considered to  be a subtype of the oncocytic variant. A 35-year-old female sought consult for assessment of a painless right neck tumor. Fine-needle aspiration biopsy report was given as hashimotos thyroiditis with hurthe cell neoplasm . The patient underwent right hemithyroidectomy. Grossly a single lobe of thyroid which was nodular on external surface and cut surface there was a single nodule measuring   1 cm in diameter,whitish in appearance with few areas of congestion. Microscopically, the tumor was composed of papillae lined by cells with eosinophilic cytoplasm, nuclear chromatin clearing, grooves, and pseudoinclusions and a characteristic lymphoplasmacytic infiltrate of the papillae cores. At places the thyroid parenchyma shows follicles of vaying sizes along with lymphoid follicles.

References

1. Zubair W. Baloch M ,Virginia A. Warthin-like Papillary Carcinoma of the Thyroid Arch Pathol Lab Med 2000;124 :26-28
2. Yeo M N, Bae J S, Lee S, Kim M, Lim D. The Warthin-Like Variant of Papillary Thyroid Carcinoma:A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis, International Journal of Endocrinology 2015;1:34-36
3. Colunga K ,Solis A, Falcón L A, Quintana O A. Warthin-Like Papillary Thyroid Carcinoma Associated with Lymphadenopathy and Hashimoto's Thyroiditis. Case Rep Endocrinol. 2015;25:18-19
4. Paliogiannis P, Attene F, Trogu T, Trignano M .Warthin-Like Papillary Carcinoma of the Thyroid Gland:Case Reports in Oncological Medicine 2012:12;15-19
5. Robyn L, Sylvia L, LiVols S, Virginia A. Warthin-like Tumor" of the Thyroid ,American Journal of Surgical Pathology:1995:12:11-15
6. Rosai J. Rosai and Ackerman’s Surgical Pathology, Soft tissue. 10th ed. NewYork: Mosby Elsevier;2011.

Downloads

Published

04-08-2016

How to Cite

1.
Patki S, Kshirsagar GR, Yadav S, Gadgil N. Warthin like variant of Papillary carcinoma thyroid against the background of Hashimotos thyroiditis : a case report. Ann of Pathol and Lab Med [Internet]. 2016 Aug. 4 [cited 2024 Nov. 19];3(3):C138-141. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm657

Issue

Vol. 3 No. 3 (2016)

Section

Case Report

License

Copyright (c) 2016 Swati Patki, Ganesh R Kshirsagar, Sheetal Yadav, Nitin Gadgil

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).