Small Cell Carcinoma of Gallbladder: A Rare Case Report
Keywords:
Gallbladder, Small Cell Carcinoma, Neuroendocrine CarcinomaAbstract
A small cell carcinoma of the gallbladder is being reported from a young  lady of 31 years of age, for the first time from Jammu and Kashmir state. The SCC, also called Neuroendocrine carcinoma of gallbladder are comparatively very rare and are reported usually from elderly ladies but in the present case the lady was very young. The patient presented with clear cut symptoms of cholecystitis and was thus diagnosed at early stage of life, which however is not true with most of the cases, which depict symptoms very late at older age leading to their low survival rate after diagnosis.
The present report is a case of pure SCC without any association with any other disease. The patient had multiple gallstones, a mass each  in fundus and  neck of gallbladder. The left hepatic duct was partially blocked and dilated. Microscopy of stained sections of gallbladder showed tumour cells, with hyperchromatic nuclei and high N:C ratio, arranged in nests, cords and trabeculae extending up to serosa (or features suggestive of SCC). The diagnosis of SCC was also confirmed immunohistochemically. Cholecystectomy along with removal of portahepatic lymphnodes was done. The patient is undergoing chemotherapy and is showing signs of improvement.
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Copyright (c) 2016 Nidhi Gupta, Bawana Raina, Arvind Khajuria
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