An Insight Into Pituitary Fossa Lesions: A single institutional experience
Keywords:
Sellar, Pituitary, Adenoma, Craniopharyngioma, Sqaush CytologyAbstract
Introduction: The complex placement of the sellar region and the various native tissues provide a fertile ground for the development of spectrum of non-neoplastic and neoplastic lesions in this area.
Methods: The prospective study of two years in a tertiary care hospital was conducted. A total of 67 specimens of sellar and parasellar region were received from the neurosurgery department for intraoperative as well as histopathological diagnosis. Squash cytology was utilised for rapid intraoperative consultation.
Results: Pituitary adenomas were the most common tumours followed by craniopharyngiomas.
Conclusion: Multidisciplinary approach of radiology, neurosurgery and pathology helps in arriving at the right conclusion and diagnosis in central nervous system lesions.Â
References
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9) Saeger W, Lüdecke DK, Buchfelder M, Fahlbusch R, Quabbe HJ, Petersenn S. Pathohistological classification of pituitary tumours: 10 years of experience with the German pituitary tumour registry. European J Endocrinol. 2007;156: 203-216.
10) Valassi E, Biller BM, Klibanski A, Swearingen B. Clinical features of nonpituitarysellar lesions in a large surgical series. ClinEndocrinol (Oxf). 2010;73:798-807.
11) Cho HJ, Kim H, Kwak YJ, et al. Clinicopathologic Analysis of Pituitary Adenoma - A Single Institute Experience. J Korean Med Sci 2014;29:405-410.
12) Rishi A, Sharma MC, Sarkar C, Jain D, Singh M, Mahapatra AK, Mehta VS, Das TK. A clinicopathological and immunohistochemical study of clinically non-functioning pituitary adenomas: A single institutional experience. Neurology India. 2010;58:418-423.
13) Matshana, John K. Analysis of pituitary tumours: retrospective study at Chris Hani Baragwanath and Charlotte Maxeke Johannesburg academic hospitals, 1999-2008. [Available from: http://hdl.handle.net/10539/8798]
14) Plata AO, Tena-Suck ML, Neri IP, Bojórquez DR, Fernández A. Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study, Pituitary Adenomas, VafaRahimi-Movaghar (Ed.). 2012. ISBN: 978-953-51-0041-6, InTech, Available from: http://www.intechopen.com/books/pituitary-adenomas/pituitary-adenomas-clinico-pathologicalimmunohistochemical-and-ultrastructural-study
15) Mindermann T, Wilson CB. Age related and gender related occurrence of pituitary adenomas. ClinEndocrinol (Oxf). 1994;41:359-64.
16) Daly AF, Jaffrain-Rea ML, Ciccarelli A, Socin HV et al. Clinical Characterization of Familial Isolated Pituitary Adenomas. J Clin Endocrinol Metab. 2006;91:3316-3323.
17) De Mello PA, Naves LA, Neto AP, et al. Clinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas. ArqNeuropsiquiatr. 2013;71:307-312.
18) Reddy R, Cudlip S, Byrne JV, Karavitaki N, Wass JA. Can we ever stop imaging in surgically treated and radiotherapy–naïve patients with non- functioning pituitary adenoma? Eur J Endocrinol. 2011; 165:739-44
2) Kleinschmidt BK, De Masters. Pituitary gland. In: Juan Rosai, editor. Rosai and Ackerman's Surgical Pathology. 10th ed. Edinburgh. Mosby Elsevier; 2012. 2441-2461.
3) Lloyd RV, Kovacs K, Young Jr WF, et al. Tumours of the Pituitary gland. In: De Lellis RA, Lloyd RV, Heitz PU, Eng C, editors. World Health Organization Classification of Tumours. Pathology and genetics of Tumours of Endocrine Organs. Lyon, France. IARC; 2004. 10-13.
4) Scheithauer BW, Kovacs K, Horvath E, et al. Pituitary carcinoma. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, eds. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Endocrine Organs. Lyon, France. IARC Press; 2004. 36-39.
5) Rushing EJ , Giangaspero F, Paulus W, et al. Craniopharyngioma. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, eds. WHO Classification of Tumours of the Central Nervous System. Lyon, France. IARC Press; 2007. 238-240.
6) Adamson TE, Wiestler OD, Kleihues P, Yasargil MG. Correlation of clinical and pathological features in surgically treated craniopharyngiomas. J Neurosurg. 1990;73:12-17.
7) Burger PC, Scheithauer BW, Vogel FS. Region of the sella turcica. In: Surgical pathology of the Nervous system and its coverings. 4th ed. New York. Churchill Livingstone; 2001. 437-490.
8) Scheithauer BW. The Pituitary and Sellar Region. In: Mills SE, Carter D, Greenson JK, Reuter VE, Stoler MH, editors. Sternberg’s Diagnostic Surgical Pathology. 5th ed. Philadelphia. Lippincott Williams & Wilkins; 2010. 460-488.
9) Saeger W, Lüdecke DK, Buchfelder M, Fahlbusch R, Quabbe HJ, Petersenn S. Pathohistological classification of pituitary tumours: 10 years of experience with the German pituitary tumour registry. European J Endocrinol. 2007;156: 203-216.
10) Valassi E, Biller BM, Klibanski A, Swearingen B. Clinical features of nonpituitarysellar lesions in a large surgical series. ClinEndocrinol (Oxf). 2010;73:798-807.
11) Cho HJ, Kim H, Kwak YJ, et al. Clinicopathologic Analysis of Pituitary Adenoma - A Single Institute Experience. J Korean Med Sci 2014;29:405-410.
12) Rishi A, Sharma MC, Sarkar C, Jain D, Singh M, Mahapatra AK, Mehta VS, Das TK. A clinicopathological and immunohistochemical study of clinically non-functioning pituitary adenomas: A single institutional experience. Neurology India. 2010;58:418-423.
13) Matshana, John K. Analysis of pituitary tumours: retrospective study at Chris Hani Baragwanath and Charlotte Maxeke Johannesburg academic hospitals, 1999-2008. [Available from: http://hdl.handle.net/10539/8798]
14) Plata AO, Tena-Suck ML, Neri IP, Bojórquez DR, Fernández A. Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study, Pituitary Adenomas, VafaRahimi-Movaghar (Ed.). 2012. ISBN: 978-953-51-0041-6, InTech, Available from: http://www.intechopen.com/books/pituitary-adenomas/pituitary-adenomas-clinico-pathologicalimmunohistochemical-and-ultrastructural-study
15) Mindermann T, Wilson CB. Age related and gender related occurrence of pituitary adenomas. ClinEndocrinol (Oxf). 1994;41:359-64.
16) Daly AF, Jaffrain-Rea ML, Ciccarelli A, Socin HV et al. Clinical Characterization of Familial Isolated Pituitary Adenomas. J Clin Endocrinol Metab. 2006;91:3316-3323.
17) De Mello PA, Naves LA, Neto AP, et al. Clinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas. ArqNeuropsiquiatr. 2013;71:307-312.
18) Reddy R, Cudlip S, Byrne JV, Karavitaki N, Wass JA. Can we ever stop imaging in surgically treated and radiotherapy–naïve patients with non- functioning pituitary adenoma? Eur J Endocrinol. 2011; 165:739-44
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11-10-2016
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Patil PR, Bharambe BM, Sondankar D. An Insight Into Pituitary Fossa Lesions: A single institutional experience. Ann of Pathol and Lab Med [Internet]. 2016 Oct. 11 [cited 2025 Feb. 6];3(4):A289-295. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm835
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Copyright (c) 2016 Purwa Rangrao Patil, Bhavana Madhukar Bharambe, Divyaja Sondankar
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