Spectrum of endometrial lesions in patients with abnormal uterine bleeding: A histopathological study
Keywords:
Abnormal uterine bleeding, endometrial curetting, endometrial hyperplasia, endometrial carcinomaAbstract
Background: Abnormal uterine bleeding (AUB) is the most common menstrual problem in women of developing countries. Endometrial curettage followed by histopathological examination can be used for definitive diagnosis of AUB. This study was conducted to assess endometrial causes of AUB on histopathological examination and its association with different age groups presenting with AUB.
Methods: This study was conducted at Department of Pathology, Narayana medical college and hospital, Nellore, India on 264 women presenting with AUB over a period of 1 year from January to December 2015. A statistical analysis between endometrial histopathology and age of presentation was done using chi square test.
Result: Most of the patients with AUB presented in 30 -40 years age group (37.5%) with menorrhagia as the commonest bleeding pattern. The cause of AUB was determined 261 out of 264 endometrial samples as 3 specimens were inadequate for evaluation. Out of the remaining 261 cases, 223 (84.47%) cases were due to functional causes while the remaining 38 cases (14.39%) showed definite endometrial pathology (organic AUB). Endometrial causes of AUB and age of presentation showed positive association with p value <0.05.
Conclusion: Endometrial curettage is recommended in women of perimenopausal and menopausal age group presenting with AUB to rule out pre-neoplastic conditions and malignancy.
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Copyright (c) 2016 Ankita Goel, Vissa Shanthi, Nandam Mohan Rao, Parul Jain, Syam Sundara Byna, Jyothi Conjeevaram
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