Nosocomial Burn Wound Infections due to Non-Fermenting Gram Negative Bacteria: Our experiences from a tertiary care center in North India

Authors

  • Naz Perween Dept. of Microbiology, Superspeciality Pediatric Hospital and Postgraduate Teaching Institute Sector-30, NOIDA, UP-201301 India
  • S Krishna Prakash Department of Microbiology, Maulana Azad Medical College, BSZ Marg, New Delhi, India-110002
  • Prabhav Aggarwal Department of Microbiology, Maulana Azad Medical College, BSZ Marg, New Delhi, India-110002
  • Lalit Mohan Gupta Department of Microbiology, Maulana Azad Medical College, BSZ Marg, New Delhi, India-110002

Keywords:

Pseudomonas, Acinetobacter, Antimicrobial resistance, burns

Abstract

Background: Nosocomial infections contribute to up to 50% mortality in burn patients. Non fermenting Gram negative bacteria, being ubiquitous in nature, can easily colonize the burn site and subsequently cause infections. The objective of the study was to understand the role of two of the most common non-fermenters, Pseudomonas aeruginosa and Acinetobacter baumanii in nosocomial burn wound infections and determine their antimicrobial resistance pattern.

Methods: Wound swabs were collected from burn patients and cultured using standard microbiological techniques. Isolates of non-fermenters, Pseudomonas aeruginosa and Acinetobacter baumanii, were identified by conventional biochemical tests. The antibiotic susceptibility testing of these isolates were carried out by disc diffusion method.

 

Result: A total of 248 and 70 clinical strains of Pseudomonas aeruginosa and Acinetobacter baumanii were isolated, respectively. Out of these, 67.62% and 72.05% isolates of Pseudomonas aeruginosa and Acinetobacter baumannii were MDR. Pseudomonas showed highest resistance to gentamicin (83.3%), followed by ceftazidime (80.18%), and Netilmicin (76.89%). Among Acinetobacter baumanii isolates, resistance to cephalexin (98.5%) was highest, followed by gentamicin (94.6%) and cefotaxime (94.12%).

 

Conclusion: The increasing antibiotic resistance shown by these important pathogens leaves us with fewer option to treat severe life-threatening infections, stressing the need of a continuous antibiotic surveillance program and stringent implementation of infection control practices.  

 

 

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Published

06-11-2016

How to Cite

1.
Perween N, Prakash SK, Aggarwal P, Gupta LM. Nosocomial Burn Wound Infections due to Non-Fermenting Gram Negative Bacteria: Our experiences from a tertiary care center in North India. Ann of Pathol and Lab Med [Internet]. 2016 Nov. 6 [cited 2024 Nov. 19];3(5):A415-420. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm902

Issue

Vol. 3 No. 5 (2016): (Suppl) November

Section

Original Article

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Copyright (c) 2016 Naz Perween, S Krishna Prakash, Prabhav Aggarwal, Lalit Mohan Gupta

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