Bone Tumors and Tumor-like lesions: A study in a Tertiary Care Hospital, Mumbai

Authors

  • Prashant Vijay Kumavat Assitant Professor LTMMC and LTMGH sion mumbai . Mahrashtra.
  • Nitin Gadgil
  • Chetan Chaudhari
  • Ujwal Rathod
  • Ganesh Kshirsagar
  • Sangita Margam

Keywords:

Bone, Benign, Cyst, Metastasis, Tumors

Abstract

Background: Bone tumors are one of the intimidate challenge to the orthopedic surgeon. This call out for even more concern in resource poor settings, in economically developing nations. Weanalysedbone tumours and tumour like lesions, their demographic features likeage and sex distributions, anatomical sites of occurrence andtheir relative frequencies,clinico-pathological characteristics and histo-morphological features as seen in a tertiary care hospital of India.

Methods: This is a retrospective study of 10 years in our department, of 216 cases of bone tumors, including primary bone tumors, metastatic lesions and tumor like lesions.

Results: A total of 216 patients were studied aged 1 to 80 years. 114 (52.78%) patients were males and 102(47.22%) were females. Commonest bone tumor observed in our study was metastatic tumors 40/216 cases (18.52%).Commonest benign tumor in our study was osteochondroma 30/103 cases (29.13%) followed by giant cell tumor 27/103 cases (26.21 %). Commonest Primary malignant bone tumor in our study was Ewing’s tumor 11/48 cases (22.92%), followed by osteogenic sarcoma and myeloma 9 cases (18.75%) each. Fibrous dysplasia was seen to be commonly located at jaw bone and skull region 6/13 cases (46.15%) whereas aneurysmal bone cyst was located commonly at vertebra 6/10 cases (60%). Out of 40 cases of metastatic bone tumors, 15 cases (37.5%) showed metastasis from lung carcinoma, of which, non-small cell carcinoma made up of 80 % of the cases.

Conclusion: Metastatic lesion is commonest bone tumor in our study.  Commonest benign tumor was osteochondroma and giant cell tumor. Ewing’s tumor is commonest primary bone tumor and fibrous dysplasia in tumor like lesions of the bone.  


DOI: 10.21276/APALM.2017.972

 

Author Biography

Prashant Vijay Kumavat, Assitant Professor LTMMC and LTMGH sion mumbai . Mahrashtra.

Assitant Professor, Department of pathology,  LTMMC AND LTMGH SION mumbai

References

1. Fletches CD, Unni KK, Mertens F, editors. World Health Organisation Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: 1ARC Press; 2013.
2. Unni KK. Enchondroma. Dahlin's Bone Tumours: General Aspects and Data on 11,087 Cases. Philadelphia, PA: Lippincott-Raven; 1996.
3. Bamanikar SA, Pagaro PM, Kaur P, Chandanwale SS, Bamanikar A, Buch AC. Histopathological Study of Primary Bone Tumours and Tumour-Like Lesions in a Medical Teaching Hospital. JKIMSU 2015;4(2):46-55.
4. Davies AM, Sundaram M, James SJ, editors. Imaging of bone tumours and tumour-like lesions: techniques and applications. Springer Science & Business Media; 2009.
5. Kyriakos M, Land VJ, Penning HL, Parker SG: Metastatic chondroblastoma. Report of a fatal case with a review of the literature on atypical, aggressive, and malignant chondroblastoma. Cancer 1985;55:1770–89.
6. Bone RJ, Joints. In: Rosai J, editor. Ackerman's Surgical Pathology. St. Louis: Mosby; 1996. p. 1917-2020.
7. Aston W, Briggs T, Solomon L. Tumours. In: Solomon L, Warwick D, Nayagam S, editors. Apley’s System of Orthopaedics and Fractures. 9th ed. London: Hodder Arnold, Hodder education; 2010. p. 187-224.
8. Rosenberg AE. Bones, joints and soft tissue tumours. In: Kumar V, Abbas AK, Fausto N, Aster JC, editors. Robbins and cotran; Pathologic Basis of disease. 8th ed. Gurgaon: Elsevier, Reed Elsevier India private limited; 2010. p.1205-56.
9. Boffano P, Roccia F, Campisi P, Gallesio C. Review of 43 Osteoma of the Craniomaxillofacial Region. Journal of Oral and Maxillofacial Surgery. 2012; 70(5):1093-1095.
10. Feletar M. Osteoid osteoma: a case for conservative management. Rheumatology. 2002;41(5):585-586.
11. Czerniak. Dorfman and Czerniak's Bone Tumours. Elsevier; 2016.
12. Greipp PR, Raymond NM, Kyle RA, O'Fallon WM. Multiple myeloma: significance of plasmablastic subtype in morphological classification. Blood. 1985;65(2):305-10.
13. Dosoretz DE, Raymond AK, Murphy GF, Doppke KP, Schiller AL, Wang CC, Suit HD. Primary lymphoma of bone the relationship of morphologic diversity to clinical behaviour. Cancer. 1982;50(5):1009-14.
14. Tofe AJ, Francis MD, Harvey WJ. Correlation of neoplasms with incidence and localization of skeletal metastases: An analysis of 1,355 diphosphonate bone scans. Journal of nuclear medicine: official publication, Society of Nuclear Medicine. 1975;16(11):986-989.
15. Jain K, Ravishankar R, Rupakumar CS, Gadiyar HB, Manjunath GV. Bone tumours in a tertiary care hospital of south India: a review 117 cases. Indian Journal of Medical and Paediatric Oncology. 2011;32(2):82.
16. Sugiura H, Yamada K, Sugiura T, Hida T, Mitsudomi T. Predictors of survival in patients with bone metastasis of lung cancer. Clinical orthopaedics and related research. 2008;466(3):729-36.
17. Norman A, Ulin R. A Comparative Study of Periosteal New-Bone Response in Metastatic Bone Tumours (Solitary) and Primary Bone Sarcomas 1. Radiology. 1969;92(4):705-708.linical behaviour. Cancer. 1982;50(5):1009-14.
18. Mohammed A, Isa HA. Pattern of primary tumours and tumour-like lesions of bone in Zaria, Northern Nigeria. West African journal of medicine. 2007;26(1):37-41

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Published

03-02-2017

How to Cite

1.
Kumavat PV, Gadgil N, Chaudhari C, Rathod U, Kshirsagar G, Margam S. Bone Tumors and Tumor-like lesions: A study in a Tertiary Care Hospital, Mumbai. Ann of Pathol and Lab Med [Internet]. 2017 Feb. 3 [cited 2024 Dec. 27];4(1):A10-18. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm972

Issue

Vol. 4 No. 1 (2017)

Section

Original Article

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Copyright (c) 2017 Prashant Vijay Kumavat, Nitin Gadgil, Chetan Chaudhari, Ujwal Rathod, Ganesh Kshirsagar, Sangita Margam

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