A Comparative Study between Conventional and Bethesda System for Reporting Thyroid Cytopathology
DOI:
https://doi.org/10.21276/apalm.1840Keywords:
FNAC, TBSRTC, Thyroid glandAbstract
Background: Disorders of thyroid gland are very common. Thyroid cancers comprise 1% of all malignancies, and are the most common cancer of endocrine system. It is more common in females as compared to males.
Method: 51 Patients with enlarged thyroid gland were studied. All the thyroid FNAC cases were reported and compared by using both the conventional and the Bethesda System for Reporting Thyroid Cytopathology (TBSTRC). The conventional system includes description of the microscopic findings of the case along with a final impression at the end. In equivocal cases, the differentials were given. However, for statistical analysis, the reporting system was modified into five category system. The categories were-1) Inadequate 2) Benign 3) Equivocal 4) Follicular 5) Malignant
Results:The age at presentation of the patient varied widely from 10 years to 100 years. The mean age of presentation is 40 years. There was female preponderance amongst the patients (94.1% females). In the vast majority of the cases TBSRTC is equivalent to the conventional system in the pattern of reporting.
Conclusion: TBSRTC may be viewed as a better screening test for thyroid lesions. Follicular patterned lesions pose the greatest difficulty in evaluating thyroid FNAC smears with their being significant overlap in the cytological features of different lesions.
References
DeLellis RA, Lloyd RV, Heitz PU, Eng C editors: WHO classification of Tumors: Pathology and genetics of tumors of endocrine organa. Lyon: International agency for research of cancer. IARC press 2004.
Layfield LJ, Morton MJ, Cramer HM, Hirschowitz S. Implications of the proposed thyroid fine-needle aspiration category of "follicular lesion of undetermined significance": A five-year multi-institutional analysis. Diagn Cytopathol. 2009 Oct;37(10):710-4.
Cibas ES, Ali SZ. The Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol. 2009;132:658–665
Wu HH, Rose C, Elsheikh TM. The Bethesda system for reporting thyroid cytopathology: An experience of 1,382 cases in a community practice setting with the implication for risk of neoplasm and risk of malignancy. Diagn Cytopathol. 2012 May;40(5):399-403.
Theoharis CG, Schofield KM, Hammers L, Udelsman R, Chhieng DC. The Bethesda thyroid fine-needle aspiration classification system: year 1 at an academic institution. Thyroid. 2009 Nov;19(11):1215-23.
Bongiovanni M, Spitale A, Faquin WC, Mazzucchelli L, Baloch ZW. The Bethesda System for Reporting Thyroid Cytopathology: a meta-analysis. Acta Cytol. 2012;56(4):333-9. doi: 10.1159/000339959.
Ali SZ, Cibas ES. The Bethesda System for Reporting Thyroid Cytopathology: definitions, criteria and Explnanatory Notes. New York: Springer; 2010
Jo VY, Stelow EB, Dustin SM, Hanley KZ. Malignancy risk for fine-needle aspiration of thyroid lesions according to the Bethesda System for Reporting Thyroid Cytopathology. Am J Clin Pathol. 2010 Sep;134(3):450-6.
Baloch ZW, Fleisher S, LiVolsi VA, Gupta PK. Diagnosis of "follicular neoplasm": a gray zone in thyroid fine-needle aspiration cytology. Diagn Cytopathol. 2002 Jan;26(1):41-4.
Baloch ZW, LiVolsi VA, Asa SL, Rosai J, Merino MJ, Randolph G, Vielh P, DeMay RM, Sidawy MK, Frable WJ. Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science Conference. Diagn Cytopathol. 2008 Jun;36(6):425-37. doi: 10.1002/dc.20830.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2018 Shabana Azad, Shaila N Shah, Rekha R Iyer
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
