Squamoid Eccrine Ductal Carcinoma: A Diagnostic

Authors

  • Bhavna Sharma PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi
  • Purnima Malhotra department of pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi
  • Minakshi Bhardwaj department of pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi

DOI:

https://doi.org/10.21276/apalm.1909

Keywords:

Squamoid, Eccrine, Ductal, Carcinoma, p63, CEA

Abstract

Eccrine carcinomas comprise less than 0.01% of all cutaneous malignancies. Squamoid eccrine ductal carcinoma is an exceedingly rare variant that exhibits both squamous and eccrine ductal characteristics. It presents in patients older than 50 years on the head, neck, and trunkas nodule or plaque. It is commonly misdiagnosed as squamous cell carcinoma from which it must be differentiated as its recurrence and metastasis rates are much higher.Very few cases have been reported, we hereby report an additional case of this rare tumor.

A 50 years old male presented with a slow-growing  nodule in the frontal region of scalp since one year. Histopathology showed a dermal based infiltrativeepithelial tumor with extensive squamous differentiation arranged in interlacing cords and nests, with focal formation of ductal lumina which was highlighted by immunohistochemistry. The diagnostic identification of eccrine carcinomas is hampered by their rarity .Awareness of this rare entity will help in accurate diagnosis and management.

Author Biographies

Bhavna Sharma, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi

Department of Pathology, Senior Resident

Purnima Malhotra, department of pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi

MD Pathology, Specialist

Minakshi Bhardwaj, department of pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi

MD Pathology, Professor and head of department, Department of pathology

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Published

27-08-2018

How to Cite

1.
Sharma B, Malhotra P, Bhardwaj M. Squamoid Eccrine Ductal Carcinoma: A Diagnostic. Ann of Pathol and Lab Med [Internet]. 2018 Aug. 27 [cited 2024 Dec. 27];5(8):C119-121. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/1909

Issue

Section

Case Report