Histo-Morphological Spectrum of Paranasal Sinus Tumours
A Three Year Study
Keywords:
Paranasal sinus tumours, Benign tumour, Malignant tumour, histopathology
Abstract
BACKGROUND: Maxillary, Ethmoid, Sphenoid and Frontal sinuses constitute the paranasal sinuses. Paranasal sinus tumours are highly diverse and uncommon tumours of all head and neck neoplasms. Large clinical studies, limited to paranasal sinus (PNS) tumours, are lacking. Despite their infrequency, they represent both a diagnostic and therapeutic challenge. Histopathological examination plays a major role in diagnosis of PNS tumours. This is a retrospective study to review the PNS tumours which were reported in an urban tertiary care hospital in South India and to highlight on some of the rare tumours occurring in this site. MATERIALS AND METHODS: Histopathological sections from 67 cases of paranasal sinus tumours were studied retrospectively for a period of 3 years from April 2015 to March 2018. The spectrum of paranasal sinus tumours were analyzed in relation with age, sex and site of common occurrence. RESULTS: The age ranged from 15 to 85 years and male: female ratio was 2:1. Most of the tumours are malignant, with benign-malignant ratio of about 1:4. Squamous cell carcinoma and its variants were predominant among malignant tumours, constituting 66% of total malignancy. Among the benign tumours, inverted papillomas were the commonest, constituting 30% of cases. CONCLUSIONS: In this study, mucoepidermoid carcinoma is the second commonest malignant tumour where as in literature Adenoid cystic carcinoma is the second commonest. The age, sex and site distribution in this study correlates with literature.References
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2. Rahman.A. Orbital complications of the paranasal sinuses disease. Transl Biomed 2015; 6:3 .doi:21767/2172-0479.100027.
3. Dulguerov P, Jacobsen MS, Allal AS, Lehmann W, Calcaterra T. Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review. Cancer 2001 Dec; 92(12):3012–29.
4. Katz TS, Mendenhall WM, Morris CG, Amdur RJ, Hinerman RW, Villaret DB. Malignant tumours of the nasal cavity and paranasal sinuses. Head Neck 2002 Sep; 24(9):821-9.
5. Kumar A, Sood N, Gautam R, Ahalwat S, Nausaran K. Histopathological Analysis of Lesion of Nasal cavity, Paranasal Sinus and Nasaopharynx-A Clinical study. J Adv Med Dent Scie Res 2017; 5(11):90-2.
6. Uma R, Mehraj Banu OA. Histopathological study of nasal mass –A study of 110 cases. IJSciAndTech2016; 19(1):98-102.
7. Satarkar, Srikanth S. Tumour and tumour like conditions of the nasal cavity, paranasal sinuses and nasopharynx: A study of 206 cases .Indian J Cancer 2016; 53:478-82.
8. Maru AM , Patel UV , Shrivatsav A, Lakum NR, Choksi TS , Agnihotri AS. Histopathology study of nasal masses in patients coming to tertiary care hospital:A study of 70 cases. Med J DY Patil Univ 2015;8:468-73.
9. Gangwar N, Balakrishnan R, Nayak DR, Mahesh SG. Transitional cell carcinoma of Paranasal sinuses-Significance. Indian JAppl Res 2014 April; IV(IV):426-28.
10. Jhonson CD et al. Malignant lymphoma of the maxillary sinus. J Am Osteopath Assoc 1993 Feb; 93(2):252-8.
11. Michel G et al Adenoid cystic carcinoma of the paranasal sinuses: retrospective series and review of the literature. Eur Ann Otorhinolaryngol Head Neck Dis2013; 130(5):257-62.
12. Angiero F, Borloni R, Macchi M, Stefani M. Ameloblastic Carcinoma of the Maxillary Sinus .Anticancer Res 2008; 28:3847-54.
13. Hunchaisri N. Myxoma of the nasal cavity and paranasal sinuses: report of a case. N J Med Assoc Thai 2002; 85(1):120-4.
14. Azarpira N, Ashraf MJ, Monabati A, Alireza Makrempour, Bijan Khademi, Elham Abedi et al. Primary Lymphoma of Nasal cavity and paranasal sinuses Lab Medicine 2012; 43(6):294-9.
15. Bhattacharya J, Goswami BK, Banerjee A, Bhattachayya Ranjan , Chakrabarthi I, GiriA. Clinico-pathological study of masses arising from sinonasal tract and nasopharynx in north Bengal population with special reference to neoplasm. Egypt JOtolaryngol2015; 31: 98-04.
Published
26-12-2018
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