Extra Nodal Primary Diffuse Large B-Cell Lymphoma of Thyroid

A Review of Literature

Authors

  • Anand Kalia Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai
  • Sudhamani S Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India
  • Anita Sharan Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India
  • Surekha Bhalekar Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India
  • Prakash Roplekar Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India

DOI:

https://doi.org/10.21276/apalm.2362

Keywords:

Thyroid, Lymphoma, Primary, Diffuse Large B-cell Lymphoma, DLBCL, Primary Thyroid Lymphoma

Abstract

Primary Thyroid Lymphoma (PTL) involves less than 5% of all thyroid malignancies. It mostly comes into notice later in life of which Diffuse Large B-Cell Lymphoma (DLBCL) is the commonest type. Though the primary site of lymphoma is Lymph Node, DLBCL involving thyroid primarily and later spreading to Lymph Nodes and other sites is also known. This tumor causes rapid progression of the thyroid mass which can compress the trachea and may even present as an acute emergency. Therefore, it is important to recognize this entity as the treatment and progression differs from other thyroid malignancies

We are presenting the case of Extra Nodal Primary DLBCL of Thyroid gland in a 55 years old female who presented with thyroid swelling along with multiple Cervical Lymph Nodes which on Histopathology and subsequent Immunohistochemistry was confirmed as DLBCL of primary thyroid gland with regional and distant metastases.

Author Biographies

Sudhamani S, Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India

Department of Pathology

Anita Sharan, Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India

Department of Pathology

Surekha Bhalekar, Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India

Department of Pathology

Prakash Roplekar, Dr. D. Y. Patil Medical College, Nerul, Navi Mumbai. India

Department of Pathology

References

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2. Babu KG, Lakshmaiah KC, Lokanatha D, Babu MS, Suresh TM, Rao CR, Premalata CS, Abraham LJ, Lokesh KN. Diffuse large B cell lymphoma of the thyroid: Seven cases with review of the literature from India. Oncology, Gastroenterology and Hepatology Reports. 2015 Jul 1;4(2):81-4.
3: Rosai J, Tallini G, Thyroid Gland. In. Houston M, editor. Rosai and Ackerman’s Surgical Pathology, 10th ed. United States; Elsevier Mosby; 2011. p. 535-4.
4. Vigliar E, Caleo A, Vitale M, Di Crescenzo V, Garzi A, Zeppa P. Early cytological diagnosis of extranodal stage I, primary thyroid Non-Hodgkin lymphoma in elderly patients. Report of two cases and review of the literature. BMC surgery. 2013 Oct;13(2):S49.
5. Hunt KE, Reichard KK. Diffuse large B-cell lymphoma. Archives of pathology & laboratory medicine. 2008 Jan;132(1):118-24.

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Published

17-02-2019

How to Cite

1.
Kalia A, S S, Sharan A, Bhalekar S, Roplekar P. Extra Nodal Primary Diffuse Large B-Cell Lymphoma of Thyroid: A Review of Literature. Ann of Pathol and Lab Med [Internet]. 2019 Feb. 17 [cited 2024 Dec. 27];6(2):C16-18. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/2362

Issue

Section

Case Report