Pregnancy Luteoma Mimicking Ectopic Pregnancy: A Self-Resolving Lesion Undergoing Surgical Excision
DOI:
https://doi.org/10.21276/apalm.3498Keywords:
pregnancy luteoma, ectopic pregnancy, virilizationAbstract
Pregnancy luteoma (PL) is a rare condition, characterized by solid proliferation of luteinized cells. Most patients are asymptomatic; however, virilizing symptoms are seen in 25% of cases. They are usually detected incidentally. Here, we present a case where the patient presented with 6 weeks of amenorrhoea and acute abdominal pain with a positive urine pregnancy test. Clinically, she was diagnosed as a case of ovarian ectopic pregnancy; laparotomy and later, ovariotomy were performed. On histopathology, the lesion was diagnosed as PL. Differential diagnoses include non-neoplastic conditions like ectopic pregnancy, hyperreactio luteinalis, and ovarian neoplasms. An accurate diagnosis is important since PL is a self-resolving, non-neoplastic lesion which usually does not require surgical excision.
References
1. Sternberg WH, Barclay DL. Luteoma of pregnancy. Am J Obstet Gynecol. 1966;95:165–84.
2. Shen J, Li J, Tao X, Feng Y, Li B. Antenatal diagnosis and management of pregnancy luteoma: A case report and literature review. Medicine (Baltimore). 2023;102(30):e34521.
3. Bhardwaj S, Kalir T. Pregnancy luteoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ovarypregnancyluteoma.html. Accessed 2024 Dec 22.
4. Verma V, Paul S, Chahal KS, Singh J. Pregnancy luteoma: A rare case report. Int J App Basic Med Res. 2016;6:282–3.
5. Stewart I, Twidale E. Pregnancy luteoma. BMJ Case Rep. 2024;17:e261239.
6. Gilks B. Rosai and Ackerman’s Surgical Pathology. Philadelphia: Elsevier; 2018. p. 1372–3.
7. Brar RK, Bharti JN, Nigam JS, Sehgal S, Singh HP, Ojha P. Pregnancy luteoma in ectopic pregnancy: A case report. J Reprod Infertil. 2017;18(3):333–5.
8. Beksac S, Selçuk I, Boyraz G, Güner G, Turgal M, Usubutun A. Two patients with marginal symptoms showing hyperthecosis at the edge of malignancy: Presentation of two cases. J Turk Ger Gynecol Assoc. 2013;14(3):182–5.
9. Shang JH, Huang CX, Zheng Q, Feng JL, He K, Xie HN. Imaging features, clinical characteristics and neonatal outcomes of pregnancy luteoma: A case series and literature review. Acta Obstet Gynecol Scand. 2024;103:740–50.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Arun Gopal
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
