Fine Needle Aspiration Cytology Of Cervical Lymphadenopathy: Is There Anything Different At South Coastal Region Of India?

Authors

  • Priya R PG student,,Department of pathology,,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry 607402
  • Dhananjay Shrikant Kotasthane Department of Pathology,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry
  • Vaishali Dhananjay Kotasthane Department of Pathology,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry
  • Koteeswaran G Department of Pathology,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry

Keywords:

Fine needle aspiration cytology, lymph node, histopathology

Abstract

Background: Cervical lymphadenopathy is one of the commonest clinical presentations of the patients in all age groups. FNAC is simple, inexpensive and minimally invasive procedure that can be used as an outpatient procedure for diagnosing lymphadenopathy cases.

Aims and Objective: To assess the various causes of cervical lymphadenopathy through FNAC and to see the distribution of various lesions with respect to age and gender and to correlate with histopathological findings.

Materials and Methods: The present Analytical cross-sectional study was conducted in the Department of Pathology, Mahatma Gandhi Medical College and Hospital, Pondicherry from January 2010 to July 2016.FNAC was done by standard procedure. All the slides were reviewed and diagnosis was rendered. Cytology findings were compared with histopathological diagnosis where-ever excision biopsy was done.

Results: A total of 411 patients were included in the present study. Overall, female preponderance was seen. In benign non-neoplastic lesions, peak occurrence was seen in the 3rd decade, whereas it was 7th decade in metastatic lesions. Benign lymphadenopathies were diagnosed in 75.1% of cases, majority being chronic reactive lymphadenitis(34.6%) followed by granulomatous lymphadenitis(30%). The proportion of granulomatous lymphadenitis was more in our study as compared to other studies(p<0.0001).In neoplastic lesions, majority (88%)were metastatic deposits. In metastatic lesions, higher proportion of metastatic thyroid carcinoma (13.9%) was  seen which was statistically significant (p<0.0001) as compared to other studies. Unpaired t test was used to prove statistical significance. Cyto-histopathology correlation was done in 54 cases and FNAC showed sensitivity of  97%,specificity 95%and diagnostic accuracy of 96%.

Conclusion: FNAC is safe, simple, rapid, minimally invasive and inexpensive procedure to diagnosis cervical lymphadenopathy with high sensitivity, specificity and diagnostic accuracy. Higher frequency of granulomatous lesions was seen in non-neoplastic cases. In neoplastic lesions, metastatic thyroid carcinoma showed higher frequency in our study conducted at iodine sufficient south coastal region of India. 

 

DOI: 10.21276/APALM.1463

Author Biographies

Priya R, PG student,,Department of pathology,,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry 607402

PG student,,Department of pathology,,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry 607402

Dhananjay Shrikant Kotasthane, Department of Pathology,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry

Professor and HOD,Department of pathology,,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry 607402

Vaishali Dhananjay Kotasthane, Department of Pathology,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry

Assistant Professor,Department of pathology,,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry 607402

Koteeswaran G, Department of Pathology,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry

Professor,Department of pathology,,Mahatma Gandhi Medical College and Research Institute,Pillaiyarkuppam,Pondicherry-Cuddalore Main road,Pondicherry 607402

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Published

01-09-2017

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1.
R P, Kotasthane DS, Kotasthane VD, G K. Fine Needle Aspiration Cytology Of Cervical Lymphadenopathy: Is There Anything Different At South Coastal Region Of India?. Ann of Pathol and Lab Med [Internet]. 2017 Sep. 1 [cited 2024 Nov. 19];4(4):A460-465. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1463

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Vol. 4 No. 4 (2017)

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Original Article

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Copyright (c) 2017 Priya R, Dhananjay Shrikant Kotasthane, Vaishali Dhananjay Kotasthane, Koteeswaran G

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